Kark Jeremy D, Fink Rita, Adler Bella, Goldberger Nehama, Goldman Sylvie
Epidemiology Unit, Hadassah Medical Organization and Hebrew University-Hadassah School of Public Health and Community Medicine, Ein Kerem, Jerusalem 91120, Israel.
Int J Epidemiol. 2006 Apr;35(2):448-57. doi: 10.1093/ije/dyl012. Epub 2006 Feb 2.
Lifestyle factors relevant to coronary risk factors differ between Palestinians and Israelis. Both have been exposed, albeit differently, to the stressors of the long-term conflict. We determined the incidence of coronary heart disease, previously unreported in Palestinians, in these Mediterranean populations and made international comparisons with the MONICA Programme.
We applied the rigorous World Health Organization MONICA protocol, which enables standardized international population-based comparisons, to determine all acute myocardial infarction events and coronary deaths among Palestinians and Israelis aged 25-74, residents of the Jerusalem district in 1997.
We confirmed a total of 265 coronary events among 76,200 Arabs and 698 among 226,500 Jews. Rates among Arabs were substantially higher than in Jews, particularly so in women. Age-adjusted rate ratios (RRs) for coronary events were 1.58 [95% confidence interval (95% CI) 1.34-1.87] among men and 2.37 (95% CI 1.81-3.10) among women. When restricted to coronary deaths, Arab: Jewish RRs were 2.79 (95% CI 2.09-3.73) in men and 2.66 (95% CI 1.77-4.00) in women. Compared with MONICA populations in 20 countries, Arabs ranked first in total coronary event rates and first in non-fatal myocardial infarction rates, exceeded populations in Finland, Scotland, and Northern Ireland, and showed striking differences from the participating Mediterranean centres.
Coronary risk appears to be particularly high in Palestinian Arabs. Determinants of these unexpected findings should be sought and prevention programmes initiated.
与冠心病风险因素相关的生活方式因素在巴勒斯坦人和以色列人之间存在差异。尽管方式不同,但两者都长期受到冲突压力的影响。我们确定了这些地中海人群中冠心病的发病率(此前巴勒斯坦人中未报告过),并与莫尼卡项目进行了国际比较。
我们采用了严格的世界卫生组织莫尼卡方案,该方案能够进行标准化的基于国际人群的比较,以确定1997年耶路撒冷地区25 - 74岁的巴勒斯坦人和以色列人中所有急性心肌梗死事件和冠心病死亡情况。
我们在76200名阿拉伯人中确认了265例冠心病事件,在226500名犹太人中确认了698例。阿拉伯人的发病率显著高于犹太人,女性尤为如此。男性冠心病事件的年龄调整率比(RR)为1.58[95%置信区间(95%CI)1.34 - 1.87],女性为2.37(95%CI 1.81 - 3.10)。当仅限于冠心病死亡时,阿拉伯人与犹太人的RR在男性中为2.79(95%CI 2.09 - 3.73),在女性中为2.66(95%CI 1.77 - 4.00)。与20个国家的莫尼卡项目人群相比,阿拉伯人在冠心病总发病率和非致命性心肌梗死发病率方面排名第一,超过了芬兰、苏格兰和北爱尔兰的人群,并且与参与研究的地中海中心人群存在显著差异。
巴勒斯坦阿拉伯人冠心病风险似乎特别高。应寻找这些意外发现的决定因素并启动预防计划。