Ambro Christine M, Humphreys Tatyana R, Lee Jason B
Department of Cutaneous Dermatology and Cutaneous Biology, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA.
Am J Dermatopathol. 2006 Feb;28(1):60-2. doi: 10.1097/01.dad.0000157460.72334.fa.
We describe an epidermotropically metastatic pancreatic mucinous ductal adenocarcinoma on the scalp. Neoplastic glandular structures that varied in size and shape containing abundant mucin within the lumens and in the neoplastic cells were present within a seborrheic keratosis and adjacent normal epidermis. Similar neoplastic glandular structures were present in the dermis, some within adnexal epithelium and lymphatic vessels. The patient's history of pancreatic mucinous ductal adenocarcinoma and immunohistochemical staining pattern of carbohydrate antigen 19-9 (CA 19-9) confirmed the diagnosis.
我们描述了一例发生于头皮的向表皮转移的胰腺黏液性导管腺癌。在脂溢性角化病及相邻正常表皮内可见大小和形状各异的肿瘤性腺管结构，管腔内及肿瘤细胞内含有丰富黏液。真皮内也存在类似的肿瘤性腺管结构，部分位于附属器上皮和淋巴管内。患者的胰腺黏液性导管腺癌病史及糖类抗原19-9（CA 19-9）免疫组化染色模式证实了诊断。
