Kaoutzanis Christodoulos, Chang Myungwon C, Abdul Khalek Feras J, Kreske Edward
Department of Surgery, Saint Joseph Mercy Health System, Ann Arbor, Michigan, USA.
BMJ Case Rep. 2013 Jan 9;2013:bcr2012007931. doi: 10.1136/bcr-2012-007931.
Pancreatic adenocarcinoma is one of the deadliest human malignancies with the majority of cases diagnosed late in the course of the disease. Cutaneous metastases originating from pancreatic cancer are rare. The most common site reported is the umbilicus. Non-umbilical cutaneous metastases are far less common with only a few cases reported in the literature. Our case involved a 43-year-old man with pancreatic carcinoma who was offered resection and a Whipple procedure was planned. Intraoperatively, the patient was found to have a widely metastatic disease not seen on preoperative imaging. Postoperatively, cutaneous metastasis in the scalp was discovered. Although rare, the recognition of non-umbilical cutaneous metastases of pancreatic adenocarcinoma can be of value because they can not only detect an underlying tumour but also guide management.
胰腺腺癌是最致命的人类恶性肿瘤之一，大多数病例在疾病晚期才被诊断出来。源自胰腺癌的皮肤转移很少见。报道的最常见部位是脐部。非脐部皮肤转移极为罕见，文献中仅报道了少数病例。我们的病例是一名43岁的胰腺癌男性患者，原本计划进行切除手术及惠普尔手术。术中发现患者患有广泛转移疾病，术前影像学检查未显示。术后，发现头皮出现皮肤转移。尽管罕见，但认识到胰腺腺癌的非脐部皮肤转移可能具有价值，因为它们不仅可以检测出潜在肿瘤，还能指导治疗。
