Doyle E, Herbert E N, Bunce C, Williamson T H, Laidlaw D A H
St. Thomas' Hospital, Lambeth Palace Road, London, SE1 7EH, UK.
Eye (Lond). 2007 Apr;21(4):534-40. doi: 10.1038/sj.eye.6702260. Epub 2006 Feb 3.
To determine factors associated with anatomical and functional outcomes of macula-off retinal detachment surgery in a modern vitreoretinal unit.
A retrospective casenote review of 185 patients presenting with macula-off retinal detachment was performed. Demographic and ocular characteristics were determined. Logistic regression analysis was used to determine (1) the effect of these factors on visual outcome and (2) their effect on primary and final anatomical success.
Primary and ultimate anatomical success were achieved in 76 and 84% of cases. Patients with oil in at final follow-up were considered to be anatomical failures. Statistically significant factors predicting primary anatomical success using a multiple variable model were preoperative logMAR visual acuity, preoperative PVR and number of breaks. Preop logMAR visual acuity and duration of macular detachment were the statistically significant factors predicting ultimate success. In all, 44% of patients regained 6/12 Snellen or better with a median improvement of 0.78 logMAR. For prediction of visual outcome (in patients with no ocular comorbidity) only preoperative logMAR visual acuity achieved statistical significance (P=0.001) at the P=0.05 level.
In all, 76% of macula-off detachments may be repaired with one operation and 44% of patients regain at least 6/12 Snellen. The median logMAR acuity increment of 0.78 far exceeds that seen in cataract surgery. Preoperative visual acuity is the most important factor predicting primary and final anatomical success as well as visual outcome. Preoperative PVR, number of breaks and duration of detachment also affect outcomes.
确定现代玻璃体视网膜治疗中心黄斑脱离视网膜脱离手术的解剖和功能预后相关因素。
对185例黄斑脱离视网膜脱离患者进行回顾性病例记录 review。确定人口统计学和眼部特征。采用逻辑回归分析来确定(1)这些因素对视力预后的影响,以及(2)它们对初次和最终解剖学成功的影响。
76%和84%的病例分别实现了初次和最终解剖学成功。最终随访时眼内有硅油的患者被视为解剖学失败。使用多变量模型预测初次解剖学成功的统计学显著因素为术前logMAR视力、术前增殖性玻璃体视网膜病变(PVR)和裂孔数量。术前logMAR视力和黄斑脱离持续时间是预测最终成功的统计学显著因素。总体而言,44%的患者视力恢复到6/12 Snellen或更好,logMAR中位数改善0.78。对于视力预后的预测(在无眼部合并症的患者中),仅术前logMAR视力在P = 0.05水平具有统计学显著性(P = 0.001)。
总体而言,76%的黄斑脱离可通过一次手术修复,44%的患者视力至少恢复到6/12 Snellen。logMAR视力中位数提高0.78远远超过白内障手术所见。术前视力是预测初次和最终解剖学成功以及视力预后的最重要因素。术前PVR、裂孔数量和脱离持续时间也会影响预后。