[神经源性肺水肿：一项基于观察的前瞻性研究]
[Neurogenic pulmonary edema: a prospective study based on observation].
作者信息
Akinci Ozkan I, Eker Aylin, Erdem Tülin, Yildirim Ayşe, Sencer Altay, Esen Figen, Cakar Nahit
机构信息
Department of Anesthesiology and Reanimation, Istanbul University, Istanbul Medical Faculty, Istanbul, Turkey.
出版信息
Ulus Travma Acil Cerrahi Derg. 2006 Jan;12(1):22-5.
BACKGROUND
In this study, we evaluated the cause and the clinical course of neurogenic pulmonary edema which has developed abruptly in some of the patients in the neurosurgical intensive care unit.
METHODS
We evaluated 223 patients in the neurosurgical ICU (116 males; 107 females; mean age 44.4+/-19.5). Five of these had worsening in neurological evaluation and oxygenation and were diagnosed as having a neurogenic pulmonary edema. Patients with pneumonia were excluded from the study.
RESULTS
We identified acute hydrocephaly in three patients and re-bleeding of an aneurysm in one as the cause of neurogenic pulmonary edema. No cause could be identified in the remaining patient. Although four patients could be discharged from the ICU, one died due to multiorgan failure.
CONCLUSION
Physicians should be careful about neurogenic pulmonary edema, a life-threatening clinical condition, that develops within hours of a neurologic event and usually resolves with neurologic recovery.
背景
在本研究中，我们评估了神经外科重症监护病房中部分患者突然发生的神经源性肺水肿的病因及临床病程。
方法
我们评估了神经外科重症监护病房的223例患者（116例男性；107例女性；平均年龄44.4±19.5岁）。其中5例患者神经功能评估及氧合情况恶化，被诊断为神经源性肺水肿。肺炎患者被排除在研究之外。
结果
我们确定3例患者的病因是急性脑积水，1例患者的病因是动脉瘤再出血，为神经源性肺水肿的病因。其余患者未发现病因。尽管4例患者可从重症监护病房出院，但1例因多器官功能衰竭死亡。
结论
医生应警惕神经源性肺水肿，这是一种危及生命的临床病症，在神经系统事件发生数小时内出现，通常随神经功能恢复而缓解。
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