Di Matteo Adele, Bonivento Daniele, Tsernoglou Demetrius, Federici Luca, Cervone Felice
Dipartimento di Biologia Vegetale, Universita' di Roma "La Sapienza", Piazzale Aldo Moro 5, 00185 Roma, Italy.
Phytochemistry. 2006 Mar;67(6):528-33. doi: 10.1016/j.phytochem.2005.12.025. Epub 2006 Feb 3.
Polygalacturonase-inhibiting proteins are plant extracellular leucine-rich repeat proteins that specifically bind and inhibit fungal polygalacturonases. The interaction with PGIP limits the destructive potential of polygalacturonases and might trigger the plant defence responses induced by oligogalacturonides. A high degree of polymorphism is found both in PGs and PGIPs, accounting for the specificity of different plant inhibitors for PGs from different fungi. Here, we review the structural features and our current understanding of the PG-PGIP interaction.
多聚半乳糖醛酸酶抑制蛋白是植物细胞外富含亮氨酸重复序列的蛋白，可特异性结合并抑制真菌多聚半乳糖醛酸酶。与多聚半乳糖醛酸酶抑制蛋白（PGIP）的相互作用限制了多聚半乳糖醛酸酶的破坏潜力，并可能触发由寡聚半乳糖醛酸苷诱导的植物防御反应。在多聚半乳糖醛酸酶（PGs）和多聚半乳糖醛酸酶抑制蛋白（PGIPs）中均发现了高度多态性，这解释了不同植物抑制剂对来自不同真菌的多聚半乳糖醛酸酶（PGs）的特异性。在此，我们综述了多聚半乳糖醛酸酶（PG）-多聚半乳糖醛酸酶抑制蛋白（PGIP）相互作用的结构特征以及我们目前的认识。
