Beck B D
Gradient Corporation, 20 University Road, Cambridge, MA 02138, USA.
Hum Exp Toxicol. 2006 Jan;25(1):3-5. doi: 10.1191/0960327106ht577oa.
A full presentation of relevant information, including both non-adverse and beneficial effects, of chemicals is important to developing sound and balanced risk assessments. Such considerations are not new. For example, the American Thoracic Society has developed criteria for defining adverse and non-adverse pulmonary effects. Failing to allow risk assessors to even consider non-adverse and beneficial effects will discourage the use of information from developing technologies, such as genomics, and from new understandings of dose-response relationships, as reflected in the hormetic model. Failing to provide such information to risk managers potentially provides a biased perspective on risk.
全面呈现化学品的相关信息，包括非有害和有益影响，对于开展合理且平衡的风险评估至关重要。此类考量并非新鲜事物。例如，美国胸科学会已制定了定义有害和非有害肺部影响的标准。不让风险评估者考虑非有害和有益影响，将会阻碍利用诸如基因组学等新兴技术所产生的信息，以及阻碍利用剂量反应关系的新认识，如在 hormetic 模型中所体现的那样。不向风险管理者提供此类信息，可能会使他们对风险形成有偏差的看法。
