Chutka Darryl S, Takahashi Paul Y, Hoel Robert W
Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
Essent Psychopharmacol. 2005;6(6):331-40.
Medications are commonly used in the elderly population. Because of a variety of treatments now available, many disease states now have very effective treatment. As a result, our elderly patients often take multiple medications. Due to various changes that occur, the elderly are at increased risk of adverse drug effects and drug toxicity potentially resulting in serious complications. Some medications have a greater potential to cause harm and these should be made aware to those who prescribe to elderly patients. Some of these medications should not be used if at all possible, while others, if used, need to be used with great caution, watching carefully for signs of problems. This article describes a variety of medications which have an increased potential for causing harm in elderly patients and gives alternatives of safer medications consideration.
药物在老年人群中普遍使用。由于现在有各种各样的治疗方法,许多疾病状态现在都有非常有效的治疗手段。因此,我们的老年患者经常服用多种药物。由于发生的各种变化,老年人出现药物不良反应和药物毒性的风险增加,这可能会导致严重的并发症。一些药物造成伤害的可能性更大,应该让为老年患者开处方的人了解这些情况。其中一些药物应尽可能避免使用,而其他药物如果使用,则需要非常谨慎,仔细观察问题迹象。本文介绍了多种在老年患者中造成伤害可能性增加的药物,并给出了更安全药物的替代选择以供考虑。