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[When "deprescribing" drugs can improve the elderly patient's health].

作者信息

Queneau Patrice, Doucet Jean, Paille François

机构信息

Service de médecine interne gériatrique, CHU de Rouen, Secrétaire général de l'APNET.

出版信息

Bull Acad Natl Med. 2007 Feb;191(2):271-82; discussion 282-5.

Abstract

Elderly people are frequently prescribed unnecessary and/or dangerous medications. The resulting polymedication carries four types of risk : an increased risk of adverse drug events (ADEs), decreased benefits of appropriate drugs, decreased compliance with appropriate treatments, and increased cost. Physicians should thus, when possible, deprescribe, reduce, replace or withdraw inappropriate medications. This article examines the following questions: Which medications can be stopped? What are the risks? How best to withdraw undesirable drugs? What are the potential health benefits for elderly people? When should drugs not be deprescribed? How to promote controlled trials aimed at optimizing the duration of treatments, especially in elderly people? and How to educate prescribers, pharmacists and patients in deprescription?

摘要

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