Mouzopoulos George, Stamatakos Mihalis, Vasiliadis George, Skandalakis Panagiotis
Sparta Hospital, Sparta and Laiko Hospital, Athens, Greece.
Acta Orthop Belg. 2005 Dec;71(6):743-5.
We present a rare case of spontaneous rupture of the adductor longus tendon induced by ciprofloxacin. A 35-year-old man was diagnosed with pneumonia and was recommended ciprofloxacin 500 mg iv twice a day for 7 days. Three days after receiving the initial dose, he developed discomfort in his left medial thigh, and pain and swelling in the same area followed ten days later. He consulted us when he noted a palpable mass on the medial side of his left thigh, and MRI study revealed adductor longus tendon rupture. There was no obvious underlying disease or other factor causing fragility of his adductor longus tendon. We review the pathophysiological mechanisms leading to fluoroquinolone-related tendon rupture as well as the risk factors and discuss proper management.
我们报告一例罕见的由环丙沙星引起的内收长肌腱自发性断裂病例。一名35岁男性被诊断为肺炎，建议静脉注射环丙沙星500毫克，每日两次，共7天。在接受首剂药物三天后，他感到左大腿内侧不适，十天后该区域出现疼痛和肿胀。当他注意到左大腿内侧有一个可触及的肿块时前来咨询我们，磁共振成像研究显示内收长肌腱断裂。没有明显的基础疾病或其他导致其内收长肌腱脆弱的因素。我们回顾了导致氟喹诺酮类药物相关肌腱断裂的病理生理机制以及危险因素，并讨论了适当的处理方法。
