Matzkin Valeria B, Geissler Catherine, Coniglio Raul, Selles Juana, Bello Mabel
King's College London, Department Nutrition and Dietetics, UK.
Int J Psychiatr Nurs Res. 2006 Jan;11(2):1283-93.
Argentinean women have one of the highest international mortality rates for cardiovascular disease and they are particularly vulnerable to eating pathologies. Cardiovascular risk is exacerbated in women with Anorexia Nervosa (AN), since high cholesterol concentrations have been widely reported.
To compare blood cholesterol concentrations in AN patients with controls, and to correlate cholesterol with the body mass index (BMI), patient age, vomiting and tobacco.
Cholesterol measurements documented at diagnosis from the clinical notes of patients were recorded from the Association Against Bulimia and Anorexia (ALUBA). Comparison was carried out with data of the general Argentinean public.
Total cholesterol, LDL and HDL concentrations were higher in patients compared with controls. Total cholesterol in patients decreased during treatment and it was correlated with the patient age, but with no other variable.
The abnormal lipid profile places patients at risk for cardiovascular disease. Older and untreated patients may be at particular higher risk of suffering from the consequences of elevated cholesterol concentrations.
阿根廷女性的心血管疾病国际死亡率位居前列，且她们尤其容易出现饮食方面的病症。神经性厌食症（AN）女性的心血管风险会加剧，因为已有大量报道称她们的胆固醇浓度较高。
比较AN患者与对照组的血液胆固醇浓度，并将胆固醇与体重指数（BMI）、患者年龄、呕吐情况和吸烟情况进行关联分析。
从阿根廷抗贪食症和厌食症协会（ALUBA）记录的患者临床笔记中获取诊断时记录的胆固醇测量值。与阿根廷普通公众的数据进行比较。
与对照组相比，患者的总胆固醇、低密度脂蛋白（LDL）和高密度脂蛋白（HDL）浓度更高。患者的总胆固醇在治疗期间下降，且与患者年龄相关，但与其他变量无关。
异常的血脂状况使患者面临心血管疾病风险。年龄较大且未接受治疗的患者可能尤其更容易遭受胆固醇浓度升高带来的后果。
