Hosoe Tomoo, Itabashi Takeshi, Kobayashi Nao, Udagawa Shun-ichi, Kawai Ken-ichi
Faculty of Pharmaceutical Sciences, Hoshi University, Tokyo, Japan.
Chem Pharm Bull (Tokyo). 2006 Feb;54(2):185-7. doi: 10.1248/cpb.54.185.
Three new type indoloditerpenes, emindoles PA (1), PB (2), and PC (3), were isolated from the mycelium of Emericella purpurea along with the sesterterpenes variecolol and variecolactone, and the dicyanide derivatives epurpurins A to C. The structures of 1-3 were confirmed by the spectroscopic investigation. The structure of emindoles PA (1) was revised from our preliminary report. Emindoles PA (1), PB (2), and PC (3) are the indoloditerpenes having a new type of carbon skeleton.
从紫红斑节霉的菌丝体中分离出三种新型吲哚二萜类化合物,即埃米吲哚PA(1)、PB(2)和PC(3),同时还分离出了倍半萜类化合物变色醇和变色内酯,以及二氰化物衍生物紫红斑菌素A至C。通过光谱研究确定了1-3的结构。埃米吲哚PA(1)的结构已根据我们的初步报告进行了修订。埃米吲哚PA(1)、PB(2)和PC(3)是具有新型碳骨架的吲哚二萜类化合物。