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用干扰素α-2b和利巴韦林治疗一名患有X连锁淋巴增殖综合征患者的丙型肝炎病毒感染。

Treatment of HCV infection with interferon alpha-2b and ribavirin in a patient with X-linked lymphoproliferative syndrome.

作者信息

Strnad-Trojan Nicola, Linde Richard, Reichenbach Janine, Trojan Jörg, Zeuzem Stefan, Zielen Stefan

机构信息

Department of Paediatrics, Johann Wolfgang Goethe University Medical Centre, Frankfurt am Main, Germany.

出版信息

Eur J Pediatr. 2006 May;165(5):348-50. doi: 10.1007/s00431-005-0062-3. Epub 2006 Feb 4.

DOI:10.1007/s00431-005-0062-3
PMID:16463052
Abstract

Chronic hepatitis C (HCV) infection in patients with primary immunodeficiency increases the risk of an accelerated progression of HCV-related liver disease. Here, we report a patient with X-linked lymphoproliferative syndrome infected with HCV and Epstein-Barr virus (EBV). After combination treatment with interferon alpha-2b and ribavirin, clearance of HCV-RNA was achieved, and noteworthily, EBV DNA also became undetectable.

摘要

原发性免疫缺陷患者的慢性丙型肝炎病毒（HCV）感染会增加HCV相关肝病加速进展的风险。在此，我们报告一名患有X连锁淋巴增殖综合征且感染了HCV和爱泼斯坦-巴尔病毒（EBV）的患者。在接受干扰素α-2b和利巴韦林联合治疗后，实现了HCV-RNA的清除，值得注意的是，EBV DNA也变得检测不到了。

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Epstein-Barr virus infections: prospects for treatment.爱泼斯坦-巴尔病毒感染：治疗前景
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Eradication of Epstein-Barr virus by allogeneic bone marrow transplantation: implications for sites of viral latency.异基因骨髓移植对爱泼斯坦-巴尔病毒的清除：对病毒潜伏部位的影响
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