Davis J C, Dougados M, Braun J, Sieper J, van der Heijde D, van der Linden S
Division of Rheumatology, University of California San Francisco, San Francisco, California, USA.
Ann Rheum Dis. 2006 Nov;65(11):1518-20. doi: 10.1136/ard.2005.044834. Epub 2006 Feb 7.
The concept and definition of disease duration in patients with ankylosing spondylitis is ambiguous, and often many years pass between the onset of symptoms and diagnosis. Members of the Assessment in Ankylosing Spondylitis (ASAS) International Working Group by consensus recently recommended identifying specific components of the medical history to better define and document the concept of disease duration. These include (1) the time of onset of the first symptoms of axial manifestations (including inflammatory back pain); (2) the time of onset of the first symptoms of each individual manifestation, which may be an extra-axial sign or symptom of ankylosing spondylitis, such as peripheral arthritis and enthesitis; (3) the time of onset of associated diseases belonging to the spondyloarthritides, in particular acute anterior uveitis, inflammatory bowel disease and psoriasis; and (4) the time since actual diagnosis by a healthcare provider. Such uniformity in data collection will ensure comparability across studies and facilitate future research.
强直性脊柱炎患者疾病持续时间的概念和定义尚不明确，症状出现与诊断之间往往相隔数年。强直性脊柱炎评估（ASAS）国际工作组的成员最近经共识推荐确定病史中的特定组成部分，以更好地定义和记录疾病持续时间的概念。这些包括：（1）轴向表现（包括炎性背痛）的首个症状出现时间；（2）每种个体表现的首个症状出现时间，这可能是强直性脊柱炎的轴外体征或症状，如外周关节炎和附着点炎；（3）属于脊柱关节炎的相关疾病的发病时间，特别是急性前葡萄膜炎、炎症性肠病和银屑病；以及（4）自医疗服务提供者实际诊断以来的时间。数据收集的这种一致性将确保各研究之间具有可比性，并便于未来的研究。
