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重症监护病房中耐甲氧西林金黄色葡萄球菌(MRSA)医院感染发生率的降低:莫匹罗星软膏治疗及洗必泰沐浴对MRSA鼻腔携带者的作用

Reduction in incidence of nosocomial methicillin-resistant Staphylococcus aureus (MRSA) infection in an intensive care unit: role of treatment with mupirocin ointment and chlorhexidine baths for nasal carriers of MRSA.

作者信息

Sandri Ana Maria, Dalarosa Micheline Gisele, Ruschel de Alcantara Luciana, da Silva Elias Laura, Zavascki Alexandre Prehn

机构信息

Infection Control Department, Hospital São Lucas da Pontifícia Universidade Católica do Rio Grande do Sul, 6690 Ipiranga Avenue, Porto Alegre, RS 90610-000, Brazil.

出版信息

Infect Control Hosp Epidemiol. 2006 Feb;27(2):185-7. doi: 10.1086/500625. Epub 2006 Feb 8.

DOI:10.1086/500625
PMID:16465636
Abstract

After the introduction of routine treatment for every nasal carrier of methicillin-resistant Staphylococcus aureus, active follow-up surveillance for nosocomial methicillin-resistant S. aureus infection was conducted for 5 years in an intensive care unit of a tertiary-care teaching hospital. There was a significant decrease in the incidence of nosocomial methicillin-resistant S. aureus infection during the later years of follow-up. Decolonization of nasal carriers of methicillin-resistant S. aureus is probably associated with such findings.

摘要

在对每例耐甲氧西林金黄色葡萄球菌鼻腔携带者实施常规治疗后,一家三级教学医院的重症监护病房对医院获得性耐甲氧西林金黄色葡萄球菌感染进行了为期5年的主动随访监测。在随访后期,医院获得性耐甲氧西林金黄色葡萄球菌感染的发生率显著下降。耐甲氧西林金黄色葡萄球菌鼻腔携带者的去定植可能与这些结果有关。

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