Angeles-Agdeppa Imelda, Paulino Lourdes S, Ramos Adelisa C, Etorma Unita Marie, Cavalli-Sforza Tommaso, Milani Silvano
Food and Nutrition Research Institute, Department of Science and Technology, Bicutan, Taguig, Manila, Philippines.
Nutr Rev. 2005 Dec;63(12 Pt 2):S116-25. doi: 10.1301/nr.2005.dec.s116-s125.
The effectiveness of weekly iron-folic acid supplements promoted through a government-industry partnership was assessed in pregnant and non-pregnant women in the Philippines. Compliance to both weekly and daily supplementation increased during the year-long study period, but was highest with weekly supplementation. Serum ferritin and hematocrit increased significantly, whereas the hemoglobin level showed minimal change, probably because of lack of other heme-forming nutrients such as vitamin A. Serum ferritin increments were significantly higher in women taking the iron-folic acid supplements for more than 6 weeks. Weekly iron-folic acid supplementation should be recommended as a preventive strategy to control iron deficiency among reproductive-age women in the Philippines.
通过政府与行业合作推广的每周铁叶酸补充剂对菲律宾孕妇和非孕妇的有效性进行了评估。在为期一年的研究期间，每周和每日补充剂的依从性均有所提高，但每周补充剂的依从性最高。血清铁蛋白和血细胞比容显著增加，而血红蛋白水平变化最小，这可能是由于缺乏其他形成血红素的营养素，如维生素A。服用铁叶酸补充剂超过6周的女性血清铁蛋白增加显著更高。应建议将每周补充铁叶酸作为控制菲律宾育龄妇女缺铁的预防策略。
