Gergely L, Czeglédy J, Váczi L, Szabó B, Binder L, Szalka A
Acta Microbiol Acad Sci Hung. 1975;22(2):75-82.
Children free from infectious disease have been examined by indirect immunofluorescence for the presence of antibodies to the intracellular capsid antigen of Epstein-Barr virus (EBV). In the first year of life 46%, between 2 and 6 years of age 66%, and between 7 and 14 years 91%, of the children proved positive. The corresponding percentages for the presence of antibodies to cytomegalovirus (CMV) and herpes simplex virus were about 50%, irrespective of the children's age. Serum samples from 69 patients suffering from infectious mononucleosis (IM) were tested for anti-EBV antibodies. Of the 29 Paul-Bunnell-positive patients 22 had antibodies, 11 of them in high titres (greater than 1 : 80). Of the 40 Paul-Bunnell-negative cases only 21 had antibodies, 8 in high titres. Of the Paul-Bunnell-negative cases, 73% were found to have anti-CMV antibodies, 32% in high titre. The respective percentages for the Paul-Bunnell-positive cases were 42% and 10%.
对无传染病的儿童进行了间接免疫荧光检查，以检测其是否存在针对爱泼斯坦 - 巴尔病毒（EBV）细胞内衣壳抗原的抗体。在1岁儿童中，46%检测为阳性；2至6岁儿童中，66%检测为阳性；7至14岁儿童中，91%检测为阳性。无论儿童年龄如何，针对巨细胞病毒（CMV）和单纯疱疹病毒的抗体存在率相应百分比约为50%。对69例传染性单核细胞增多症（IM）患者的血清样本进行了抗EBV抗体检测。在29例保罗 - 邦内尔试验阳性的患者中，22例有抗体，其中11例为高滴度（大于1:80）。在40例保罗 - 邦内尔试验阴性的病例中，只有21例有抗体，8例为高滴度。在保罗 - 邦内尔试验阴性的病例中，73%被发现有抗CMV抗体，32%为高滴度。保罗 - 邦内尔试验阳性病例的相应百分比分别为42%和10%。
