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[拉莫三嗪所致中毒性表皮坏死松解症]

[Toxic epidermal necrolysis caused by lamotrigine].

作者信息

Rodríguez-Blanco Isabel, Sánchez-Aguilar Dolores, Toribio Jaime

机构信息

Servicio de Dermatología, Complejo Hospitalario Universitario, Facultad de Medicina, San Francisco s/n, 15782 Santiago de Compostela, Spain.

出版信息

Actas Dermosifiliogr. 2005 Mar;96(2):116-8. doi: 10.1016/s0001-7310(05)73049-0.

Abstract

Toxic epidermal necrolysis (TEN) is a serious entity consisting of a generalized eruption with the formation of flaccid blisters. It affects at least 30 % of the cutaneous surface and is usually related to the prior ingestion of medications. We describe TEN symptoms related to the introduction of lamotrigine, an anti-epileptic drug prescribed in this case for the prevention of migrainous episodes.

摘要

中毒性表皮坏死松解症(TEN)是一种严重病症,表现为全身性皮疹并伴有松弛性水疱形成。它累及至少30%的皮肤表面,通常与之前服用药物有关。我们描述了与拉莫三嗪引入相关的TEN症状,在此病例中,拉莫三嗪是一种用于预防偏头痛发作而开具的抗癫痫药物。

相似文献

1
[Toxic epidermal necrolysis caused by lamotrigine].[拉莫三嗪所致中毒性表皮坏死松解症]
Actas Dermosifiliogr. 2005 Mar;96(2):116-8. doi: 10.1016/s0001-7310(05)73049-0.
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Prolonged toxic epidermal necrolysis due to Lamotrigine.拉莫三嗪所致的迁延性中毒性表皮坏死松解症。
Clin Exp Dermatol. 2000 Jun;25(4):349-51. doi: 10.1046/j.1365-2230.2000.00655-2.x.
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Lamotrigine and toxic epidermal necrolysis.拉莫三嗪与中毒性表皮坏死松解症
Lancet. 1996 Oct 12;348(9033):1041. doi: 10.1016/S0140-6736(05)64979-3.

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