Rodríguez-Blanco Isabel, Sánchez-Aguilar Dolores, Toribio Jaime
Servicio de Dermatología, Complejo Hospitalario Universitario, Facultad de Medicina, San Francisco s/n, 15782 Santiago de Compostela, Spain.
Actas Dermosifiliogr. 2005 Mar;96(2):116-8. doi: 10.1016/s0001-7310(05)73049-0.
Toxic epidermal necrolysis (TEN) is a serious entity consisting of a generalized eruption with the formation of flaccid blisters. It affects at least 30 % of the cutaneous surface and is usually related to the prior ingestion of medications. We describe TEN symptoms related to the introduction of lamotrigine, an anti-epileptic drug prescribed in this case for the prevention of migrainous episodes.
中毒性表皮坏死松解症(TEN)是一种严重病症,表现为全身性皮疹并伴有松弛性水疱形成。它累及至少30%的皮肤表面,通常与之前服用药物有关。我们描述了与拉莫三嗪引入相关的TEN症状,在此病例中,拉莫三嗪是一种用于预防偏头痛发作而开具的抗癫痫药物。