Jeter D D, Vest G R, Buday S J
Department of Surgery, Mount Carmel Medical Center, Columbus, Ohio.
Am Surg. 1991 Jul;57(7):431-3.
Guidewire-directed biopsy is the predominant method of evaluating nonpalpable breast lesions detected by mammography. It is an accurate and safe procedure for obtaining a histologic evaluation of abnormal tissue, leading to early diagnosis and improved survival rates. This report reviews 526 needle localizations and biopsies of nonpalpable breast lesions performed in two community hospitals over a 39-month period and compares early results with those achieved in the last 13 months of the study. This review indicates that as experience in using this modality increased, the cancer detection rate increased and the percentage of invasive cancers decreased. The percentage of cancers detected in the final 13 months of the study (19%, Group II) was higher than in the first 26 months of the study (13%, Group I). Although microcalcifications were found in 24 per cent of the mammograms leading to a diagnosis of cancer, they did not prove to be a reliable indicator of malignancy in this study.
导丝引导下活检是评估乳腺钼靶检查发现的不可触及乳腺病变的主要方法。它是获取异常组织组织学评估的准确且安全的程序，有助于早期诊断并提高生存率。本报告回顾了两家社区医院在39个月内对526例不可触及乳腺病变进行的针定位和活检，并将早期结果与研究最后13个月的结果进行了比较。该回顾表明，随着使用这种方式的经验增加，癌症检出率上升，浸润性癌症的比例下降。研究最后13个月（第二组，19%）检测出的癌症百分比高于研究的前26个月（第一组，13%）。尽管在24%导致癌症诊断的乳腺钼靶片中发现了微钙化，但在本研究中它们并未被证明是恶性肿瘤的可靠指标。
