Thompson W R, Bowen J R, Dorman B A, Pricolo V E, Shahinian T K, Soderberg C H
Department of Surgery, Rhode Island Hospital, Brown University Program in Medicine, Providence 02902.
Arch Surg. 1991 Jun;126(6):730-3; discussion 733-4. doi: 10.1001/archsurg.1991.01410300076011.
A malignancy rate of 24% was achieved as a result of needle localizations and biopsies of 548 nonpalpable mammographically detected breast lesions in 507 consecutive patients during a 5-year period. Malignancy was present in 74 (23.8%) of 311 irregular soft-tissue densities, in 40 (19.6%) of 204 cases with clustered microcalcifications, and in 33 cases (54.5%) when both features were present. Same-day admission and discharge were achieved in 491 patients and local anesthesia supplemented with intravenous sedation was used in 73 (74%) of the 98 patients (in 1989) by the end of the study period. Nonpalpable cancers were categorized pathologically as stage 0 in 25 patients (20.8%), stage I in 67 patients (55.8%), stage IIA in 24 patients (20.0%), and stage IIB in four patients (3.3%). The malignancy rate rose sharply from the fourth to the fifth decade.
