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C肽对长期1型糖尿病患者胃排空的急性影响。

Acute effects of C-peptide on gastric emptying in longstanding type 1 diabetes.

作者信息

Stevens Julie E, Russo Antonietta, Delaney Carol A, Collins Peter J, Horowitz Michael, Jones Karen L

机构信息

Dept. of Medicine, University of Adelaide, Royal Adelaide Hospital, North Terrace, Adelaide, SA 5000, Australia.

出版信息

Clin Auton Res. 2006 Feb;16(1):55-7. doi: 10.1007/s10286-006-0308-9.

DOI:10.1007/s10286-006-0308-9
PMID:16477496
Abstract

Gastric emptying (GE) of a solid (100 g beef) and liquid (150 ml 10 % dextrose) meal was measured in eight patients with type 1 diabetes during intravenous infusion of C-peptide (6 pmol/kg/ min) or isotonic saline. C-peptide had no effect on either solid or liquid GE.

摘要

在8例1型糖尿病患者静脉输注C肽（6 pmol/kg/分钟）或等渗盐水期间，测量了他们对固体餐（100克牛肉）和液体餐（150毫升10%葡萄糖）的胃排空情况。C肽对固体或液体胃排空均无影响。

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本文引用的文献

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Diabet Med. 2004 Dec;21(12):1304-9. doi: 10.1111/j.1464-5491.2004.01340.x.
2
Impaired gastric emptying and altered intragastric meal distribution in diabetes mellitus related to autonomic neuropathy?糖尿病自主神经病变相关的胃排空受损及胃内食物分布改变？
Dig Dis Sci. 2003 Jun;48(6):1027-34. doi: 10.1023/a:1023779224320.
3
A longitudinal study of gastric emptying and upper gastrointestinal symptoms in patients with diabetes mellitus.
Curr Diab Rep. 2006 Dec;6(6):417-23. doi: 10.1007/s11892-006-0073-0.
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Am J Med. 2002 Oct 15;113(6):449-55. doi: 10.1016/s0002-9343(02)01228-7.
4
Human C-peptide dose dependently prevents early neuropathy in the BB/Wor-rat.人C肽可剂量依赖性地预防BB/Wor大鼠的早期神经病变。
Int J Exp Diabetes Res. 2001;2(3):187-93. doi: 10.1155/edr.2001.187.
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Gastric emptying in diabetes: clinical significance and treatment.糖尿病患者的胃排空：临床意义与治疗
Diabet Med. 2002 Mar;19(3):177-94. doi: 10.1046/j.1464-5491.2002.00658.x.
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Diabetologia. 2001 Jul;44(7):889-97. doi: 10.1007/s001250100570.
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