Johnston M A, Carachi R, Lindop G B, Leckie B
Department of Surgical Paediatrics, Royal Hospital for Sick Children, Glasgow, Scotland.
J Pediatr Surg. 1991 May;26(5):613-4. doi: 10.1016/0022-3468(91)90720-e.
A prospective study of four children with nephroblastoma has demonstrated elevation of plasma inactive renin levels at the time of detection of recurrent disease. Three of the four children had been shown to have elevated inactive renin levels at their initial presentation with primary nephroblastoma. These levels returned to normal following operation and chemotherapy. The observation provides further evidence that plasma inactive renin may be a useful tumour marker for nephroblastoma.
一项对四名肾母细胞瘤患儿的前瞻性研究表明，在复发性疾病检测时血浆无活性肾素水平升高。这四名患儿中有三名在初次诊断原发性肾母细胞瘤时就已显示无活性肾素水平升高。这些水平在手术和化疗后恢复正常。该观察结果进一步证明血浆无活性肾素可能是肾母细胞瘤的一种有用的肿瘤标志物。
