Yip Helena T, Leonard Rebecca, Kendall Katherine A
Department of Otolaryngology-Head and Neck Surgery, University of California at Davis, Sacramento, California 95817-2207, USA.
Laryngoscope. 2006 Jan;116(1):93-6. doi: 10.1097/01.mlg.0000184526.89256.85.
The development of a cricopharyngeal dysfunction is associated with a hypertonic cricopharyngeus (CP) muscle. Therefore, CP myotomy has been advocated by some authors to be an essential part of repair of this condition. However, little objective data exists to show that there is improvement in the upper esophageal sphincter (UES) after CP myotomy. This study assesses the impact of CP myotomy on UES opening.
Prospective.
Twenty patients treated at a university tertiary care center for cricopharyngeal dysfunction between 1998 and 2003 were identified. All patients underwent CP myotomy with or without Zenker's diverticulectomy. These patients had videofluoroscopic swallow studies before and after repair. The values of UES opening for 3 mL boluses from pre- and postrepair studies were compared with each other as well as with normal controls. Sixty percent (12/20) of the patients had a Zenker's diverticulum. Of these 12 patients, 5 had undergone previous attempts at surgical correction. Cricopharyngeal myotomy by way of an external approach, with or without Zenker's diverticulectomy, was performed in all patients by the senior author.
Before Zenker's diverticulectomy and CP myotomy, the mean UES opening (n = 20) for a 3 mL bolus was 0.30 cm +/- 0.17, which was 57% of the mean of 60 normal controls (0.52 cm +/- 0.15) (P < .001). After repair, the mean UES opening for the same bolus size improved to 0.51 cm +/- 0.16 (P < .0001). The UES opening size in patients who have undergone repair is comparable with that of the normal controls (P > .05).
UES opening size in patients with cricopharyngeal dysfunction is 57% of the size in normal controls. CP myotomy helps to normalize the UES opening in cricopharyngeal dysfunction repair.
环咽肌功能障碍的发生与环咽肌(CP)高张力有关。因此,一些作者主张CP肌切开术是修复这种情况的重要组成部分。然而,几乎没有客观数据表明CP肌切开术后食管上括约肌(UES)有改善。本研究评估CP肌切开术对UES开放的影响。
前瞻性研究。
确定1998年至2003年间在大学三级医疗中心接受治疗的20例环咽肌功能障碍患者。所有患者均接受了CP肌切开术,部分患者同时进行或未进行Zenker憩室切除术。这些患者在修复前后均进行了视频荧光吞咽研究。将修复前后研究中3毫升团块的UES开放值相互比较,并与正常对照组进行比较。60%(12/20)的患者有Zenker憩室。在这12例患者中,5例曾尝试过手术矫正。所有患者均由资深作者通过外部入路进行环咽肌切开术,部分患者同时进行或未进行Zenker憩室切除术。
在进行Zenker憩室切除术和CP肌切开术之前,3毫升团块的平均UES开放值(n = 20)为0.30 cm +/- 0.17,为60例正常对照组平均值(0.52 cm +/- 0.15)的57%(P <.001)。修复后,相同团块大小的平均UES开放值提高到0.51 cm +/- 0.16(P <.0001)。接受修复的患者的UES开放大小与正常对照组相当(P >.05)。
环咽肌功能障碍患者的UES开放大小为正常对照组的57%。CP肌切开术有助于使环咽肌功能障碍修复中的UES开放正常化。