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用于环咽肌功能障碍的扩大性颈段食管肌层切开术

Extended cervical esophagomyotomy for cricopharyngeal dysfunction.

作者信息

Orringer M B

出版信息

J Thorac Cardiovasc Surg. 1980 Nov;80(5):669-78.

PMID:6776351
Abstract

Forty adult patients have undergone a 7 to 10 cm cervical esophagomyotomy (from the superior cornu of the thyroid cartilage to behind the clavicle) for cricopharyngeal dysfunction. A Zenker's diverticulum was present in 12 patients (30%) and in five was recurrent. Preoperative symptoms included cervical dysphagia (85%), expectoration of saliva (40%), and intermittent hoarseness (30%). Four patients were being fed through tubes because of total inability to swallow. "Heartburn" was experienced by one half of the patients, but only 12 had acid or food regurgitation. The duration of symptoms ranged from 1 month to 11 years (average 3.9 years). Weight loss had occurred in 15 patients (38%) and ranged from 5.5 to 40.9 kg (average 16 kg). Barium swallows showed no abnormalities in 10 patients. Abnormal findings included a Zenker's diverticulum (12), prominent cricopharyngeal sphincter (11), nasopharyngeal reflux or incoordinated initiation of deglutition, or both (seven), a sliding hiatal hernia (11), and abnormal esophageal motility (seven). Esophageal manometry revealed abnormalities of upper esophageal sphincter (UES) function in only 16 patients. Of 36 patients undergoing standard acid reflux testing, one third had moderate-to-severe gastroesophageal reflux. Seven patients underwent staple resection of a Zenker's diverticulum at the time of cervical esophagomyotomy. Postoperative complications included transient vocal cord paresis (four), vocal cord paralysis (one), and salivary fistula (one). There were no postoperative deaths. After 2 to 48 months (average 16 months) of follow-up, 34 patients (85%) have had a good to excellent result, and six (15%) have not been benefited by operation.

摘要

40例成年患者因环咽肌功能障碍接受了7至10厘米的颈段食管肌层切开术(从甲状软骨上角至锁骨后方)。12例患者(30%)存在Zenker憩室,其中5例为复发性。术前症状包括颈部吞咽困难(85%)、唾液咳出(40%)和间歇性声音嘶哑(30%)。4例患者因完全无法吞咽而通过管饲进食。一半患者有“烧心”症状,但只有12例有胃酸或食物反流。症状持续时间从1个月至11年不等(平均3.9年)。15例患者(38%)出现体重减轻,减轻范围为5.5至40.9千克(平均16千克)。10例患者的钡餐检查未发现异常。异常发现包括Zenker憩室(12例)、明显的环咽肌括约肌(11例)、鼻咽反流或吞咽起始不协调或两者皆有(7例)、滑动性食管裂孔疝(11例)以及食管动力异常(7例)。食管测压仅在16例患者中显示出食管上括约肌(UES)功能异常。在36例接受标准酸反流测试的患者中,三分之一有中度至重度胃食管反流。7例患者在颈段食管肌层切开术时接受了Zenker憩室的吻合器切除术。术后并发症包括短暂性声带麻痹(4例)、声带瘫痪(1例)和唾液瘘(1例)。无术后死亡病例。经过2至48个月(平均16个月)的随访,34例患者(85%)效果良好至极佳,6例(15%)手术未获益。

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