Allen Jacqui, Yeom Brian, Saleem Shakeela, Hammond Rebecca, Miles Anna
Faculty of Medical and Health Sciences, Surgery, The University of Auckland, Auckland, New Zealand.
Department of Otolaryngology, Te Whatu Ora Health New Zealand Waitemata, New Zealand.
Laryngoscope. 2025 Aug;135(8):2713-2719. doi: 10.1002/lary.32225. Epub 2025 Apr 30.
To describe cricopharyngeal myectomy (CPMec) with Gold laser for the treatment of CP bar with Zenker's diverticulum and evaluate long-term outcomes of CPMec with Gold laser, utilizing quantitative fluoroscopic measures, dietary grading, and patient-reported metrics.
All patients undergoing CPMec with Gold laser over a 14-year period were evaluated. CPMec entails division of the diverticulum septum with removal of approximately 1 cm of muscle and mucosa. Demographic data, Eating Assessment Tool-10 scores, and videofluoroscopic swallow study (VFSS) parameters were compared pre- and postsurgery.
Eighty-four patients underwent 90 successfully completed CPMec with Gold laser. EAT-10 scores decreased from mean of 20 to 2 (SD 9, p < 0.00) following surgery. Mean opening of the pharyngoesophageal segment (PESmax) improved from 0.56 to 0.86 cm (SD 0.4, p < 0.007), pharyngeal constriction ratio (PCR) improved from 0.15 to 0.09 (SD 0.1, p < 0.000) and bolus clearance ratio (BCR) improved from 16% residue to 4% (SD 6%, p < 0.000) following surgery. Six recurrences occurred (6.7%) and all were successfully treated with further CPMec (completion rate 90/92, 98%). Four (4.4%) post-operative leaks occurred, and all were managed conservatively.
CPMec with Gold laser is safe, achievable, and provides significant symptomatic and objective improvement in swallowing for those with CP bar and Zenker's diverticulum. Removal of tissue reduces recurrence rates following CPMec and does not increase chances of adverse events.
描述使用金激光进行环咽肌切除术(CPMec)治疗伴有Zenker憩室的环咽肌条,并利用定量荧光透视测量、饮食分级和患者报告指标评估金激光CPMec的长期疗效。
对14年间接受金激光CPMec治疗的所有患者进行评估。CPMec包括切开憩室隔膜,切除约1厘米的肌肉和黏膜。比较手术前后的人口统计学数据、饮食评估工具-10评分和视频荧光吞咽造影研究(VFSS)参数。
84例患者成功接受了90次金激光CPMec治疗。术后饮食评估工具-10评分从平均20分降至2分(标准差9,p<0.00)。咽食管段平均开口(PESmax)从0.56厘米提高到0.86厘米(标准差0.4,p<0.007),咽收缩率(PCR)从0.15提高到0.09(标准差0.1,p<0.000),术后团块清除率(BCR)从残留16%提高到4%(标准差6%,p<0.000)。发生6例复发(6.7%),均通过进一步的CPMec成功治疗(完成率90/92,98%)。发生4例(4.4%)术后渗漏,均保守处理。
金激光CPMec安全、可行,对于伴有环咽肌条和Zenker憩室的患者,在吞咽方面能带来显著的症状改善和客观改善。组织切除可降低CPMec后的复发率,且不会增加不良事件的发生几率。