Borzoei S, Neovius M, Barkeling B, Teixeira-Pinto A, Rössner S
Obesity Unit M73, Department of Internal Medicine, Karolinska University Hospital, Huddinge, Stockholm, Sweden.
Eur J Clin Nutr. 2006 Jul;60(7):897-902. doi: 10.1038/sj.ejcn.1602397. Epub 2006 Feb 15.
Previous studies have indicated that fish protein may have a greater effect on satiety compared to other protein sources of animal origin.
To compare the effects of fish protein and beef protein meals on hunger and satiety.
Twenty-three normal non-smoking, healthy males aged 20-32 years, body mass index 22.5+/-1.8 (s.d.) kg/m(2) participated in a study, with within-subjects design and 1 week between test days. In the morning of the test days, subjects received a standardized breakfast. Four hours after breakfast, subjects were served an iso-energetic protein-rich (40 energy % protein) lunch meal, consisting of either a fish protein dish or a beef protein dish. Four hours after the start of the lunch meals, an ad libitum standardized evening meal was served and the intake of food was measured. Appetite was rated by visual analogue scales (VAS) immediately before and after the meals, as well as every hour between the meals. After the evening meal until bedtime, subjects were asked to record in detail foods and drinks consumed.
The repeated VAS-ratings of hunger, satiety and prospective consumption were modelled in a random effects model, taking pre-lunch VAS-ratings into account. After the fish meal, the point estimates were lower for hunger (-2+/-4.8), higher for satiety (8.7+/-6.0) and lower for prospective consumption (-4.9+/-4.7), but they did not reach statistical significance (P satiety=0.88; P hunger=0.15; P prospective=0.30). However, the energy intake at the evening meal displayed significant differences with subjects eating less after the fish protein lunch (2765 vs 3080 KJ, P<0.01) without feeling less satiated. No later energy compensation after the evening meal was found on the test day.
Although no significant differences in VAS-ratings of satiety or hunger were detected, subjects displayed an 11% reduction in energy intake at the subsequent evening meal.
先前的研究表明，与其他动物源性蛋白质来源相比，鱼类蛋白质对饱腹感的影响可能更大。
比较鱼类蛋白餐和牛肉蛋白餐对饥饿感和饱腹感的影响。
23名年龄在20 - 32岁、体重指数为22.5±1.8（标准差）kg/m²的正常不吸烟健康男性参与了一项采用受试者内设计且测试日之间间隔1周的研究。在测试日的早晨，受试者接受标准化早餐。早餐后4小时，受试者食用一份富含蛋白质（占能量的40%）且能量相等的午餐，午餐由一道鱼类蛋白菜肴或一道牛肉蛋白菜肴组成。午餐开始4小时后，提供一顿随意的标准化晚餐，并测量食物摄入量。在每顿饭前和饭后以及两餐之间的每小时，通过视觉模拟量表（VAS）对食欲进行评分。晚餐后至就寝时间，要求受试者详细记录所摄入的食物和饮料。
将午餐前的VAS评分考虑在内，采用随机效应模型对饥饿感、饱腹感和预期摄入量的重复VAS评分进行建模。食用鱼餐后，饥饿感的点估计值较低（-2±4.8），饱腹感的点估计值较高（8.7±6.0），预期摄入量的点估计值较低（-4.9±4.7），但未达到统计学显著性（饱腹感P = 0.88；饥饿感P = 0.15；预期摄入量P = 0.30）。然而，晚餐时的能量摄入量显示出显著差异，食用鱼类蛋白午餐后受试者的食量减少（2765 vs 3080千焦，P<0.01），但并未感觉饱腹感降低。在测试日，晚餐后未发现后续的能量补偿情况。
尽管在饱腹感或饥饿感的VAS评分上未检测到显著差异，但受试者在随后的晚餐时能量摄入量减少了11%。
