通过中和试验和酶联免疫吸附测定法检测实验感染兔体内的牛鼻气管炎病毒抗体。
Detection of bovine rhinotracheitis virus antibody by neutralizing test and ELISA in experimentally infected rabbits.
作者信息
Honda E, Taniguchi T, Watanabe M, Kumagai T
机构信息
Department of Veterinary Medicine, Faculty of Agriculture, Tokyo University of Agriculture and Technology, Japan.
出版信息
Zentralbl Veterinarmed B. 1991 Feb;38(1):55-9. doi: 10.1111/j.1439-0450.1991.tb00846.x.
The antibody response of rabbit to infectious bovine rhinotracheitis (IBR) virus was examined. Two rabbits were inoculated with IBR virus strain Los Angeles into the trachea and intravenously, and intravenously two times, respectively. The patterns of antibody titers in the rabbits measured by neutralization test and ELISA were similar to those in the case of bovine. The antibody was detected after the inoculation, and much more antibody was detected after the second inoculation. The fact suggests that rabbits are a very useful laboratory animal for IBR virus infection studies.
检测了兔对牛传染性鼻气管炎（IBR）病毒的抗体反应。将两只兔分别经气管和静脉接种洛杉矶株IBR病毒，另两只兔则分别静脉接种两次。通过中和试验和酶联免疫吸附测定法（ELISA）测得的兔体内抗体效价模式与牛的情况相似。接种后检测到了抗体，第二次接种后检测到的抗体更多。这一事实表明，兔是用于IBR病毒感染研究的非常有用的实验动物。
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