Matz Hagit, Orion Edith, Wolf Ronni
Dermatology Unit, Kaplan Medical Center, 76100 Rechovot, Israel.
Clin Dermatol. 2006 Mar-Apr;24(2):105-8. doi: 10.1016/j.clindermatol.2005.10.010.
The most commonly diagnosed pruritic dermatosis of pregnancy has a confusing nomenclature. The most commonly term used in the United States is pruritic urticarial papules and plaques of pregnancy (PUPPP), and in Great Britain, since 1982, polymorphic eruption of pregnancy. The etiology of PUPPP is still unknown. Placental products, hormonal alterations, and damage to connective tissue with subsequent conversion of nonantigenic molecules to antigenic ones, have been proposed as possible causes. The maternal and fetal prognosis is excellent. Treatment consists of topical or oral corticosteroids. Delivery does not usually provide relief of symptoms.
孕期最常被诊断出的瘙痒性皮肤病有一个令人困惑的命名。在美国最常用的术语是妊娠瘙痒性荨麻疹性丘疹和斑块（PUPPP），而在英国，自1982年以来则称为妊娠多形性皮疹。PUPPP的病因仍然不明。胎盘产物、激素变化以及结缔组织损伤导致非抗原性分子随后转变为抗原性分子，都被认为是可能的病因。母婴预后良好。治疗方法包括外用或口服皮质类固醇。分娩通常并不能缓解症状。
