使用光学相干断层扫描技术对正常眼睛视网膜神经纤维层厚度进行不对称性分析。
Asymmetry analysis of the retinal nerve fiber layer thickness in normal eyes using optical coherence tomography.
作者信息
Park Joon Jeong, Oh Dong Ryeul, Hong Sung Pyo, Lee Kyoo Won
机构信息
Cheil Eye Hospital, Daegu, Korea.
出版信息
Korean J Ophthalmol. 2005 Dec;19(4):281-7. doi: 10.3341/kjo.2005.19.4.281.
PURPOSE
To investigate the asymmetry of the retinal nerve fiber layer thickness (RNFLT) with respect to the horizontal and vertical meridian and between the right and left eye in normal subjects.
METHODS
The RNFLT was measured in 121 normal volunteers by optical coherence tomography (OCT). The RNFLT was analyzed by dividing the circle scanning area (diameter 3.4 mm) around the optic disc into 4 quadrants and 12 sectors.
RESULTS
There was a significant difference between the RNFLT of the nasal and temporal quadrant in individual eyes. There was a significant difference between the RNFLT of corresponding sectors with respect to the vertical or horizontal meridian in individual eyes. The nasal and temporal RNFLTs were asymmetrical between the right and left eye in the quadrant and sector analysis. The RNFLT of the nasal and temporal quadrant was thicker in the right eye. The nasal and inferior RNFLT measured by OCT had a significant correlation with degree of refractive error.
CONCLUSIONS
In normal subjects without significant anisometropia, there was significant asymmetry of the RNFLT for each eye as well as between the right and left eye.
目的
研究正常受试者视网膜神经纤维层厚度（RNFLT）相对于水平和垂直子午线以及左右眼之间的不对称性。
方法
通过光学相干断层扫描（OCT）测量121名正常志愿者的RNFLT。通过将视盘周围的圆形扫描区域（直径3.4 mm）划分为4个象限和12个扇形区域来分析RNFLT。
结果
单眼鼻侧和颞侧象限的RNFLT之间存在显著差异。单眼相应扇形区域的RNFLT相对于垂直或水平子午线存在显著差异。在象限和扇形区域分析中，左右眼之间鼻侧和颞侧的RNFLT不对称。右眼鼻侧和颞侧象限的RNFLT更厚。通过OCT测量的鼻侧和下方RNFLT与屈光不正度数有显著相关性。
结论
在没有明显屈光参差的正常受试者中，每只眼睛以及左右眼之间的RNFLT存在显著不对称性。
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