Department of Ophthalmology, Jawaharlal Postgraduate Medical Education and Research, Puducherry, India.
Indian J Ophthalmol. 2024 Aug 1;72(8):1181-1185. doi: 10.4103/IJO.IJO_203_24. Epub 2024 Jul 29.
The retinal thickness profile is essential for detecting ocular diseases like glaucoma and other optic neuropathies. The retinal nerve fiber layer (RNFL) thickness is affected by age, ethnicity, axial length, optic disc area, and inter-eye differences. Ocular dominance has a strong functional correlation with cerebral cortical activity. However, its relationship with RNFL thickness profile is yet to be fully established.
A cross-sectional study was conducted in 136 healthy adults to study the association between ocular dominance and RNFL parameters measured by Spectral domain optical coherence tomography (SD-OCT) and to study the association of ocular dominance with other parameters such as handedness, intraocular pressure, average axial length, average keratometry, and refractive error. Sighting ocular dominance was detected using the Miles test, and sensory ocular dominance was detected using the fogging test. Visual acuity and refraction assessment were done, and the patients underwent ocular biometry using the Lenstar 900 machine to measure the axial length and keratometry. The RNFL thickness was measured using the Cirrus HD optical coherence tomographer.
One hundred and thirty-two (97.06%) individuals were right-handed, four (2.94%) were left-handed, 108 (79.41%) participants were right eye dominant, and 28 (20.59%) were left eye dominant. There was 100% agreement between sighting and sensory ocular dominance. The average RNFL thickness and other measured ocular parameters were comparable in the dominant and nondominant eyes. Regardless of dominance, the left eyes in the study cohort had a greater statistically significant difference in superior RNFL thickness (P < 0.05), which correlated with increased central macular thickness.
Ocular dominance occurred mostly in the right eye. The RNFL thickness profile is not associated with ocular dominance in emmetropic and mild myopic individuals with normal best corrected visual acuity.
视网膜厚度谱对于检测青光眼和其他视神经病变等眼部疾病至关重要。视网膜神经纤维层（RNFL）厚度受年龄、种族、眼轴长度、视盘面积和双眼差异的影响。优势眼与大脑皮质活动具有很强的功能相关性。然而，它与 RNFL 厚度谱之间的关系尚未完全确定。
对 136 名健康成年人进行横断面研究，以研究优势眼与光谱域光学相干断层扫描（SD-OCT）测量的 RNFL 参数之间的关系，并研究优势眼与其他参数（如利手、眼压、平均眼轴长度、平均角膜曲率和屈光不正）的关系。使用 Miles 测试检测视力优势眼，使用 Fogging 测试检测感觉优势眼。评估视力和屈光度，并使用 Lenstar 900 机器对患者进行眼部生物测量，以测量眼轴长度和角膜曲率。使用 Cirrus HD 光学相干断层扫描仪测量 RNFL 厚度。
132 名（97.06%）个体为右利手，4 名（2.94%）为左利手，108 名（79.41%）参与者为右眼优势，28 名（20.59%）为左眼优势。视力和感觉优势眼之间有 100%的一致性。优势眼和非优势眼的平均 RNFL 厚度和其他测量的眼部参数无差异。无论优势眼如何，研究队列中的左眼在上方 RNFL 厚度上具有更大的统计学差异（P<0.05），这与中央黄斑厚度增加有关。
优势眼主要在右眼。在正常最佳矫正视力的正视和轻度近视个体中，RNFL 厚度谱与优势眼无关。
