Clark Jeremy J, Bernstein Ilene L
University of Washington, Seattle, WA 98195, USA.
Behav Neurosci. 2006 Feb;120(1):206-10. doi: 10.1037/0735-7044.120.1.206.
To examine the role of incentive sensitization in the potentiation of salt appetite by prior depletions, the authors assessed the motivation to obtain salt ("wanting") and the palatability of salt ("liking") independently in salt-sensitized rats. Breakpoint on a progressive ratio reinforcement schedule was used to measure salt wanting and taste reactivity was used to measure salt liking in rats with and without a history of Na+ depletion. Salt-sensitized rats displayed higher breakpoints relative to controls. However, a history of Na+ depletion was not associated with a greater positive shift in taste reactivity measures. The data suggest that these components of reward are separable in this model and support the general proposition that sensitization may alter wanting but not liking.
为了研究动机敏感化在先前缺盐导致盐食欲增强中的作用，作者分别评估了盐敏感大鼠获取盐的动机（“需求”）和盐的适口性（“喜好”）。采用渐进比率强化程序中的断点来测量对盐的需求，并使用味觉反应性来测量有或没有Na⁺缺乏史的大鼠对盐的喜好。与对照组相比，盐敏感大鼠表现出更高的断点。然而，Na⁺缺乏史与味觉反应性测量中更大的正向变化无关。数据表明，在该模型中奖励的这些成分是可分离的，并支持这样一个普遍观点，即敏感化可能改变需求但不改变喜好。
