γ-氨基丁酸A受体亚基mRNA在大鼠腰段脊髓中的分布。
Distribution of GABAA receptor subunit mRNAs in rat lumbar spinal cord.
作者信息
Wisden W, Gundlach A L, Barnard E A, Seeburg P H, Hunt S P
机构信息
ZMBH, Heidelberg, F.R.G.
出版信息
Brain Res Mol Brain Res. 1991 May;10(2):179-83. doi: 10.1016/0169-328x(91)90109-b.
The expression of various GABAA receptor subunit mRNAs (alpha 1, alpha 2, alpha 3, alpha 5, beta 1, beta 2, beta 3, gamma 2, delta) was studied in the adult rat lumbar spinal cord by in situ hybridization. Of these, only alpha 2, alpha 3, beta 3 and gamma 2 mRNAs are expressed at significant levels. The alpha 3, beta 3 and gamma 2 transcripts are present in many neurons throughout the Rexed laminae, whereas the alpha 2 mRNA is restricted to motor neurons and adjacent cells.
通过原位杂交技术研究了成年大鼠腰段脊髓中各种GABAA受体亚基mRNA（α1、α2、α3、α5、β1、β2、β3、γ2、δ）的表达。其中，只有α2、α3、β3和γ2 mRNA有显著表达。α3、β3和γ2转录本存在于整个Rexed板层的许多神经元中，而α2 mRNA则局限于运动神经元和相邻细胞。
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