甘青青兰根及茎的化学成分研究

[Study on the chemical constituents of roots and stems of Nardostachys chinensis].

作者信息

Liu Chun-Li, Duan Ying-Hui, Dai Yi, Yao Xin-Sheng

机构信息

Institute of Traditional Chinese Medicine and Natural Products, Jinan University, Guangzhou 510632, China.

出版信息

Zhong Yao Cai. 2011 Aug;34(8):1216-9.

PMID:22233035

Abstract

OBJECTIVE

To study the chemical constituents of roots and stems of Nardostachys chinensis.

METHODS

The chemical constituents were isolated and purified by column chromatography including silica gel, Diaion HP-20, Sephadex LH-20, ODS, and HPLC. Their structures were elucidated on the basis of spectral data analyses.

RESULTS

Six compounds were isolated and identified as 8-hydroxypinoresinol-4-O-beta-D-glucopyranoside (1), 8-hydroxypinoresinol-4'-O-beta-D-glucopyranoside (2), 8-hydroxypinoresinol-4-O-(beta-D-glucopyranosyl) 4'-O-beta-D-glucopyranoside (3), cycloolivil 6-O-beta-D-glucopyranoside(4), ferulic acid (5), chlorogenic acid methyl ester (6).

CONCLUSION

All the compounds are isolated from this genus for the first time.

摘要

目的

研究甘青青兰根和茎的化学成分。

方法

采用硅胶柱色谱、Diaion HP - 20、Sephadex LH - 20、ODS柱色谱及高效液相色谱法对化学成分进行分离纯化，并通过光谱数据分析鉴定其结构。

结果

分离鉴定出6个化合物，分别为8 - 羟基松脂醇 - 4 - O - β - D - 吡喃葡萄糖苷（1）、8 - 羟基松脂醇 - 4'- O - β - D - 吡喃葡萄糖苷（2）、8 - 羟基松脂醇 - 4 - O - （β - D - 吡喃葡萄糖基）4'- O - β - D - 吡喃葡萄糖苷（3）、环橄榄脂素6 - O - β - D - 吡喃葡萄糖苷（4）、阿魏酸（5）、绿原酸甲酯（6）。