Turner Judith A, Mancl Lloyd, Aaron Leslie A
Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA, USA Department of Rehabilitation Medicine, University of Washington School of Medicine, Seattle, WA, USA Department of Dental Public Health Sciences, University of Washington School of Dentistry, Seattle, WA, USA Department of Oral Medicine, University of Washington School of Dentistry, Seattle, WA, USA.
Pain. 2006 Apr;121(3):181-194. doi: 10.1016/j.pain.2005.11.017. Epub 2006 Feb 21.
We evaluated the short- and long-term efficacy of a brief cognitive-behavioral therapy (CBT) for chronic temporomandibular disorder (TMD) pain in a randomized controlled trial. TMD clinic patients were assigned randomly to four sessions of either CBT (n=79) or an education/attention control condition (n=79). Participants completed outcome (pain, activity interference, jaw function, and depression) and process (pain beliefs, catastrophizing, and coping) measures before randomization, and 3 (post-treatment), 6, and 12 months later. As compared with the control group, the CBT group showed significantly greater improvement across the follow-ups on each outcome, belief, and catastrophizing measure (intent-to-treat analyses). The CBT group also showed a greater increase in use of relaxation techniques to cope with pain, but not in use of other coping strategies assessed. On the primary outcome measure, activity interference, the proportion of patients who reported no interference at 12 months was nearly three times higher in the CBT group (35%) than in the control group (13%) (P=0.004). In addition, more CBT than control group patients had clinically meaningful improvement in pain intensity (50% versus 29% showed > or =50% decrease, P=0.01), masticatory jaw function (P<0.001), and depression (P=0.016) at 12 months (intent-to-treat analyses). The two groups improved equivalently on a measure of TMD knowledge. A brief CBT intervention improves one-year clinical outcomes of TMD clinic patients and these effects appear to result from specific ingredients of the CBT.
在一项随机对照试验中,我们评估了简短认知行为疗法(CBT)对慢性颞下颌关节紊乱病(TMD)疼痛的短期和长期疗效。TMD门诊患者被随机分配到接受四节CBT治疗的组(n = 79)或接受教育/注意力控制组(n = 79)。参与者在随机分组前、治疗后3个月、6个月和12个月完成了结局指标(疼痛、活动干扰、颌功能和抑郁)以及过程指标(疼痛信念、灾难化思维和应对方式)的测量。与对照组相比,CBT组在每次随访时的各项结局、信念和灾难化思维测量指标上均显示出显著更大的改善(意向性分析)。CBT组在使用放松技巧应对疼痛方面也有更大的增加,但在评估的其他应对策略的使用上则没有。在主要结局指标活动干扰方面,报告在12个月时无干扰的患者比例,CBT组(35%)几乎是对照组(13%)的三倍(P = 0.004)。此外,在12个月时,CBT组中在疼痛强度(50% 对 29% 显示减少≥50%,P = 0.01)、咀嚼颌功能(P < 0.001)和抑郁(P = 0.016)方面有临床意义改善的患者比对照组更多(意向性分析)。两组在TMD知识测量方面的改善程度相当。简短的CBT干预改善了TMD门诊患者的一年临床结局,这些效果似乎源于CBT的特定要素。