Wang Yi-qing, Saiwah David Ho, Wang Yan, Zheng Jian-tao, Jiang Hong-fei, Chen Bing-huang
Heart Center, Zhongshan Hospital affiliated to Xiamen University, Teaching Hospital of Fujian Medical University, Xiamen 361004, China.
Nan Fang Yi Ke Da Xue Xue Bao. 2006 Jan;26(1):6-10.
To evaluate the safety and efficacy of carotid artery stenting (CAS).
We prospectively evaluated the safety and efficacy of 76 carotid artery stenting (CAS) procedures in a consecutive series of 70 Chinese patients. This series represented a high-risk group that included patients with unstable angina, previous ipsilateral CEA, contralateral carotid artery occlusion, post-radiation carotid artery stenosis and other severe co-morbid conditions. The patients had independent neurological examinations before and after the procedure and follow-up cerebral angiography at 6 month.
The procedural success rate was 100%. The mean carotid artery stenosis was (82+/-18) % before and (5+/-10) % after the procedure. During the initial hospital period and 30 days after CAS, there was no major stroke but 3 minor strokes (5.7%). No myocardial infarctions or deaths occurred during or within 30 days following CAS. At a mean follow-up of 20+/-12 months, 2 patients (2.8%) had asymptomatic restenosis, and 2 non-Q wave myocardial infarction. Death occurred in 2 cases, but none of them was attributed to a neurological cause. Three patients had minor strokes and no major strokes occurred during the follow-up period.
Percutaneous carotid artery stenting is feasible for performance in Chinese patients and may lower the restenosis rate.
评估颈动脉支架置入术（CAS）的安全性和有效性。
我们前瞻性地评估了连续70例中国患者中76例颈动脉支架置入术（CAS）的安全性和有效性。该系列代表了一个高危组，包括不稳定型心绞痛患者、既往同侧颈动脉内膜切除术患者、对侧颈动脉闭塞患者、放疗后颈动脉狭窄患者以及其他严重合并症患者。患者在手术前后进行了独立的神经学检查，并在6个月时进行了随访脑血管造影。
手术成功率为100%。术前平均颈动脉狭窄为（82±18）%，术后为（5±10）%。在最初住院期间和CAS术后30天内，未发生重大卒中，但有3例轻微卒中（5.7%）。CAS期间及术后30天内未发生心肌梗死或死亡。平均随访20±12个月时，2例患者（2.8%）出现无症状再狭窄，2例发生非Q波心肌梗死。2例患者死亡，但均非神经原因所致。3例患者发生轻微卒中，随访期间未发生重大卒中。
经皮颈动脉支架置入术在中国患者中可行，且可能降低再狭窄率。
