Bailey Andrew M, Webber Mark A, Piddock Laura J V
Antimicrobial Agents Research Group, Division of Immunity and Infection, University of Birmingham, Birmingham B15 2TT, United Kingdom.
Antimicrob Agents Chemother. 2006 Mar;50(3):1071-4. doi: 10.1128/AAC.50.3.1071-1074.2006.
Analysis of expression of acrB, marA, and soxS in rich and minimal media, at early and late logarithmic growth phases, showed that acrB had increased expression in minimal medium compared to rich medium, but expression decreased dose dependently upon exposure to ciprofloxacin.
对富培养基和基本培养基中、对数生长早期和晚期的acrB、marA和soxS表达进行分析,结果表明,与富培养基相比,acrB在基本培养基中的表达增加,但在接触环丙沙星后,其表达呈剂量依赖性下降。