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Familial juvenile polyposis coli and colorectal cancer.

作者信息

O'Riordain D S, O'Dwyer P J, Cullen A F, McDermott E W, Murphy J J

机构信息

Department of Surgery, University College, Dublin, Ireland.

出版信息

Cancer. 1991 Aug 15;68(4):889-92. doi: 10.1002/1097-0142(19910815)68:4<889::aid-cncr2820680435>3.0.co;2-0.

Abstract

A 40-year-old mother and her 7-year-old son underwent colectomy for polyposis coli. Both colectomy specimens contained predominantly juvenile polyps. The mother's specimen also had numerous tubular adenomas and one 5-cm severely dysplastic villous adenoma without invasive carcinoma. Foci of adenomatous change in juvenile polyps were present in the son's specimen. The histologic features of both cases suggest a sequence of change from juvenile polyps to adenomatous polyps to cancer.

摘要

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