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两名尼日利亚人患家族性腺瘤性息肉病综合征伴结直肠癌:两例报告及文献复习

Familial adenomatous polyposis syndrome with colorectal cancer in two Nigerians: a report of two cases and review of literature.

作者信息

Bojuwoye Matthew Olumuyiwa, Olokoba Abdulfatai Bamidele, Ogunlaja Olumuyiwa Ayotunde, Agodirin Sulaiman Olayide, Ibrahim Olatunde Kazeem, Okonkwo Kenechukwu Chukwuemeka, Aliyu Aminu Mansa

机构信息

Department of Medicine, University of Ilorin Teaching Hospital, PMB 1459, Ilorin, Kwara State, Nigeria.

Department of Obstetrics and Gynaecology, Bowen University Teaching Hospital, Ogbomoso, Oyo State, Nigeria.

出版信息

Pan Afr Med J. 2018 May 4;30:6. doi: 10.11604/pamj.2018.30.6.14077. eCollection 2018.

DOI:10.11604/pamj.2018.30.6.14077
PMID:30123409
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6093594/
Abstract

Familial adenomatous polyposis syndrome is a rare condition characterized by the presence of numerous adenomatous polyps in the gastrointestinal tract and associated with risk for colorectal cancer. The disease is scarcely reported in Nigeria and this is the index report in Ilorin. Two cases were clinically diagnosed in our facility. They both presented with gastrointestinal bleeding and numerous rectal and colonic polyps were identified at colonoscopy. Histological examination of the polyps in both cases revealed features in keeping with adenomatous polyps. This report highlights the occurrence of this precancerous condition.

摘要

家族性腺瘤性息肉病综合征是一种罕见病症,其特征为胃肠道存在大量腺瘤性息肉,并伴有患结直肠癌的风险。该疾病在尼日利亚鲜有报道,这是伊洛林的首例报告。我们机构临床诊断出两例病例。他们均表现为胃肠道出血,结肠镜检查发现大量直肠和结肠息肉。两例病例息肉的组织学检查均显示符合腺瘤性息肉的特征。本报告强调了这种癌前病症的发生情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e50d/6093594/813ad7dbc28f/PAMJ-30-6-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e50d/6093594/607f73389922/PAMJ-30-6-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e50d/6093594/813ad7dbc28f/PAMJ-30-6-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e50d/6093594/607f73389922/PAMJ-30-6-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e50d/6093594/813ad7dbc28f/PAMJ-30-6-g002.jpg

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