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巴西圣保罗市西区县级监狱囚犯中的结核病

Tuberculosis in county jail prisoners in the western sector of the city of São Paulo, brazil.

作者信息

Abrahão R M C M, Nogueira P A, Malucelli M I C

机构信息

Department of Epidemiology of School of Public Health, University of São Paulo, São Paulo, Brazil.

出版信息

Int J Tuberc Lung Dis. 2006 Feb;10(2):203-8.

Abstract

SETTING

Tuberculosis (TB) status among county jail prisoners in the western sector of the city of São Paulo, Brazil.

OBJECTIVE

To estimate the prevalence of TB disease and the rate of TB infection in prisoners.

DESIGN

An observational study was conducted in 2000-2001 among 1052 prisoners in nine São Paulo county jails. After the application of an interview and tuberculin skin testing (TST), the following laboratory investigations were carried out: sputum smear examination and culture, identification and drug sensitivity testing.

RESULTS

Of 1052 prisoners, 932 underwent TST (PPD RT23 - 2TU/0.1 ml) and 64.5% were reactors. The prevalence rate of prisoners with active TB per 100,000 prisoners was 2065, around 70 times higher than among the Brazilian population and 79 times higher than in the population of the city of São Paulo. Among the 21 Mycobacterium tuberculosis strains identified, 85.7% were sensitive and 9.5% were resistant to isoniazid (INH) and rifampicin (RMP); 4.8% of the total were resistant to INH, RMP and pyrazinamide.

CONCLUSION

TB prevalence and infection rates were much higher in prisoners than among the general population.

摘要

背景

巴西圣保罗市西区县级监狱囚犯的结核病(TB)状况。

目的

估计囚犯中结核病的患病率和结核感染率。

设计

2000年至2001年对圣保罗九个县级监狱的1052名囚犯进行了一项观察性研究。在进行访谈和结核菌素皮肤试验(TST)后,开展了以下实验室检查:痰涂片检查和培养、鉴定及药敏试验。

结果

1052名囚犯中,932人接受了TST(PPD RT23 - 2TU/0.1 ml),64.5%为反应者。每10万名囚犯中活动性结核病囚犯的患病率为2065,约为巴西人口的70倍,圣保罗市人口的79倍。在鉴定出的21株结核分枝杆菌菌株中,85.7%对异烟肼(INH)和利福平(RMP)敏感,9.5%耐药;总数的4.8%对INH、RMP和吡嗪酰胺耐药。

结论

囚犯中的结核病患病率和感染率远高于普通人群。

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