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秘鲁利马公共交通部门工作人员的结核病风险。

Risk of tuberculosis in public transport sector workers, Lima, Peru.

机构信息

Grups de Recerca d'America i Africa Llatines, Unidad de Bioestadística, Facultad de Medicina, Universidad Autónoma de Barcelona, Barcelona, Spain.

出版信息

Int J Tuberc Lung Dis. 2010 Jun;14(6):714-9.

PMID:20487609
Abstract

SETTING

Delays from symptom onset to the diagnosis and treatment of smear-positive pulmonary tuberculosis (TB) produces possible new cases in persons in close contact with TB cases, especially in confined spaces such as overcrowded public transport, which puts other users and transport workers at risk.

OBJECTIVE

To estimate TB incidence rates in patients of a health micro-network, and the percentage of transport sector workers among TB and multidrug-resistant TB (MDR-TB) patients.

DESIGN

Crude and indirect standardised incidence rates of TB were calculated from an exhaustive analysis of all clinical histories of incident patients in a health micro-network between 1 January 2007 and 30 June 2008. The percentage of transport sector workers and the association between MDR-TB and working in the transport sector were analysed.

RESULTS

Standardised incidence rates for transport sector workers are 2.7-4.5 times higher than those in the total working-age male and global population of the micro-network studied. The association between TB and transport occupation and MDR-TB and transport occupation is high (respectively OR 3.06, 95%CI 2.2-4.2 and OR 3.14, 95%CI 1.1-9.1).

CONCLUSION

These results indicate that the use of informal public transport is a risk factor for TB infection and an occupational risk in countries with characteristics similar to those in Peru.

摘要

背景

从症状出现到确诊和治疗涂片阳性肺结核(TB)的延误可能会导致与 TB 病例密切接触的人产生新的病例,特别是在拥挤的公共交通工具等密闭空间中,这会使其他使用者和运输工人面临风险。

目的

估计卫生微型网络中患者的 TB 发病率,以及在 TB 和耐多药 TB(MDR-TB)患者中从事交通部门工作的比例。

设计

从 2007 年 1 月 1 日至 2008 年 6 月 30 日期间对卫生微型网络中所有新发病例的临床病史进行详尽分析,计算 TB 的粗发病率和间接标准化发病率。分析交通部门工人的比例以及 MDR-TB 与从事交通部门工作之间的关系。

结果

交通部门工人的标准化发病率比微型网络中总工作年龄男性和全球人口的发病率高 2.7-4.5 倍。TB 与交通职业以及 MDR-TB 与交通职业之间存在高度关联(分别为 OR 3.06,95%CI 2.2-4.2 和 OR 3.14,95%CI 1.1-9.1)。

结论

这些结果表明,在具有与秘鲁相似特征的国家中,使用非正规公共交通工具是 TB 感染的危险因素,也是职业风险。

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