Oyama Ken-ichi, Yamada Shozo, Usui Masaaki, Kovacs Kalman
Department of Hypothalamic & Pituitary Surgery, Toranomon Hospital, Minato-ku, Tokyo, Japan.
Pituitary. 2005;8(2):109-14. doi: 10.1007/s11102-005-3328-x.
Primary intracranial neuroblastomas are rare. They generally arise in the supratentorial parenchyma or paraventricular region. Even more rare are primary sellar neuroblastomas. We present a neuroblastoma that arose in the sellar region and mimicked a non-functioning pituitary adenoma.
This 33-year-old man presented with bitemporal hemianopsia. MRI showed a sellar mass with suprasellar extension mimicking a pituitary adenoma.
Because of tumor recurrence and dissemination to the cervical region, he underwent 6 operations and radiosurgery. Detailed histologic examination confirmed the diagnosis of neuroblastoma. Postoperative conventional radiotherapy was effective in reducing the size of the tumor.
Neuroblastoma should be considered in the differential diagnosis of patients with sellar lesions.
原发性颅内神经母细胞瘤罕见。它们通常起源于幕上实质或脑室旁区域。更为罕见的是原发性鞍区神经母细胞瘤。我们报告一例起源于鞍区并酷似无功能垂体腺瘤的神经母细胞瘤。
这名33岁男性患者出现双颞侧偏盲。磁共振成像（MRI）显示鞍区肿物并向上扩展至鞍上，酷似垂体腺瘤。
由于肿瘤复发并扩散至颈部区域，他接受了6次手术及放射外科治疗。详细的组织学检查确诊为神经母细胞瘤。术后常规放疗有效缩小了肿瘤体积。
在鞍区病变患者的鉴别诊断中应考虑神经母细胞瘤。
