Takeda Etsuko
Department of Internal Medicine, Osaka Central Hospital.
Nihon Kokyuki Gakkai Zasshi. 2006 Jan;44(1):34-8.
A 25-year-old woman presenting with acute febrile illness, progressive dyspnea, and severe hypoxemia was admitted. Chest radiography and computed tomography (CT) showed diffuse ground-glass opacities in the bilateral lung fields. Initial examination revealed SpO2 to be 90%. Oxygen was administered at a gradually increasing rate from 3L/min to a maximum of 6 L/min during the course of the same night. The eosinophil count in bronchoalveolar lavage fluid (BALF) was 5.6%. A transbronchial lung biopsy revealed alveolar septal edema, fibrin-containing exudate in airspaces, and infiltration of eosinophils into the alveolar septa. Based on these findings, we diagnosed acute eosinophilic pneumonia. Corticosteroid therapy was administered, and the abnormal shadows disappeared. She had taken a health food (Mulberry Diet) for two weeks before admission. Although a drug-induced lymphocyte stimulation test for the health food was negative, we speculated that the acute eoshinophilic pneumonia was caused by health food.
一名25岁女性因急性发热性疾病、进行性呼吸困难和严重低氧血症入院。胸部X线和计算机断层扫描(CT)显示双侧肺野弥漫性磨玻璃影。初次检查显示血氧饱和度(SpO2)为90%。在同一晚,氧气以逐渐增加的速率从3L/分钟增至最大6L/分钟。支气管肺泡灌洗液(BALF)中的嗜酸性粒细胞计数为5.6%。经支气管肺活检显示肺泡间隔水肿、气腔内含纤维蛋白的渗出物以及嗜酸性粒细胞浸润至肺泡间隔。基于这些发现,我们诊断为急性嗜酸性粒细胞性肺炎。给予了皮质类固醇治疗,异常阴影消失。她在入院前两周服用了一种保健食品(桑椹饮食)。尽管对该保健食品进行的药物诱导淋巴细胞刺激试验为阴性,但我们推测急性嗜酸性粒细胞性肺炎是由该保健食品引起的。