Saito S, Tsuneta Y, Nishiura Y, Takahashi W, Kato H, Kawai T
Department of Internal Medicine, Kohnan Hospital, Sapporo, Japan.
Nihon Kyobu Shikkan Gakkai Zasshi. 1995 May;33(5):528-32.
A 72-year-old woman was admitted to our hospital on May 7, 1990. She had suffered from dyspnea since April and complained of a continuing cough, sputum, and wheezing. A chest roentgenogram revealed bilateral, diffuse infiltration shadows, mainly in the outer zones. A considerable increase in the number of eosinophils was seen in samples of blood and of bronchoalveolar lavage fluid. Chest computed tomography showed a subpleural band-shaped infiltration shadow that was separated from normal lung fields by a subpleural curvilinear shadow. Examination of the specimen taken during open lung biopsy showed considerable eosinophil and lymphocyte infiltration, mainly in alveolar septa. No other abnormality was seen in the alveoli and there was no vasculitis or bronchiolitis. Therefore, we diagnosed this condition as chronic eosinophilic pneumonia. In addition, we discuss the subpleural curvilinear shadow.
一名72岁女性于1990年5月7日入院。自4月以来她一直呼吸困难,伴有持续咳嗽、咳痰和喘息。胸部X线片显示双侧弥漫性浸润阴影,主要位于外周区域。血液和支气管肺泡灌洗液样本中嗜酸性粒细胞数量显著增加。胸部计算机断层扫描显示胸膜下带状浸润阴影,被胸膜下曲线状阴影与正常肺野分隔开。对开胸肺活检获取的标本进行检查显示有大量嗜酸性粒细胞和淋巴细胞浸润,主要位于肺泡间隔。肺泡未见其他异常,也没有血管炎或细支气管炎。因此,我们将此病症诊断为慢性嗜酸性粒细胞性肺炎。此外,我们还讨论了胸膜下曲线状阴影。