New insecticidal antibiotics, hydroxyfungerins A and B, produced by Metarhizium sp. FKI-1079.
作者信息
Uchida Ryuji, Imasato Rie, Yamaguchi Yuichi, Masuma Rokuro, Shiomi Kazuro, Tomoda Hiroshi, Omura Satoshi
机构信息
School of Pharmaceutical Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan.
出版信息
J Antibiot (Tokyo). 2005 Dec;58(12):804-9. doi: 10.1038/ja.2005.107.
PMID:16506697
Abstract
New insecticidal antibiotics designated hydroxyfungerins A and B were isolated from the culture broth of a fungal strain Metarhizium sp. FKI-1079 together with a known compound, fungerin. The structures of hydroxyfungerins A and B were elucidated by spectroscopic studies including various NMR experiments. Hydroxyfungerins A and B showed growth inhibitory activity against brine shrimps, Artemia salina.
摘要
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