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颈动脉疾病医学治疗的新策略。

New strategies in the medical treatment of carotid artery disease.

作者信息

Rajamani Kumar, Chaturvedi Seemant

机构信息

Comprehensive Stroke Program and Department of Neurology, Wayne State University, Detroit, MI 48201, USA.

出版信息

Curr Cardiol Rep. 2006 Feb;8(1):33-7. doi: 10.1007/s11886-006-0008-z.

DOI:10.1007/s11886-006-0008-z
PMID:16507233
Abstract

Most patients with ischemic stroke or transient ischemic attack are screened for internal carotid artery stenosis. Although it is important to identify candidates for endarterectomy or stenting, the clinician must realize that most patients are not candidates for revascularization. Therefore, medical therapy remains the cornerstone of treatment. In this article, current thinking on medical therapy for carotid atherosclerosis is outlined, including aggressive use of statins, targeted blood pressure lowering, and antithrombotic therapy. Implementation of these therapies will likely reduce the need for revascularization procedures in the future.

摘要

大多数缺血性中风或短暂性脑缺血发作患者会接受颈内动脉狭窄筛查。虽然识别适合进行内膜切除术或支架置入术的患者很重要,但临床医生必须认识到,大多数患者并不适合进行血运重建。因此,药物治疗仍然是治疗的基石。本文概述了目前关于颈动脉粥样硬化药物治疗的思路,包括积极使用他汀类药物、有针对性地降低血压以及抗血栓治疗。实施这些治疗可能会减少未来血运重建手术的需求。

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本文引用的文献

1
Dose-comparison study of the combination of ezetimibe and simvastatin (Vytorin) versus atorvastatin in patients with hypercholesterolemia: the Vytorin Versus Atorvastatin (VYVA) study.依折麦布与辛伐他汀联合用药(益适纯)对比阿托伐他汀治疗高胆固醇血症患者的剂量比较研究:益适纯对比阿托伐他汀(VYVA)研究
Am Heart J. 2005 Mar;149(3):464-73. doi: 10.1016/j.ahj.2004.11.023.
2
Intensive lipid lowering with atorvastatin in patients with stable coronary disease.阿托伐他汀强化降脂治疗稳定型冠心病患者
N Engl J Med. 2005 Apr 7;352(14):1425-35. doi: 10.1056/NEJMoa050461. Epub 2005 Mar 8.
3
Statins in stroke prevention and carotid atherosclerosis: systematic review and up-to-date meta-analysis.
他汀类药物在卒中预防和颈动脉粥样硬化中的应用:系统评价与最新荟萃分析
Stroke. 2004 Dec;35(12):2902-9. doi: 10.1161/01.STR.0000147965.52712.fa. Epub 2004 Oct 28.
4
Clinical pharmacotherapy for obesity: current drugs and those in advanced development.肥胖症的临床药物治疗:现有药物及处于研发后期的药物
Curr Drug Targets. 2004 Oct;5(7):637-46. doi: 10.2174/1389450043345191.
5
Antithrombotic and thrombolytic therapy for ischemic stroke: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy.缺血性卒中的抗栓和溶栓治疗:第七届美国胸科医师学会抗栓和溶栓治疗会议
Chest. 2004 Sep;126(3 Suppl):483S-512S. doi: 10.1378/chest.126.3_suppl.483S.
6
Aspirin and clopidogrel compared with clopidogrel alone after recent ischaemic stroke or transient ischaemic attack in high-risk patients (MATCH): randomised, double-blind, placebo-controlled trial.近期缺血性卒中或短暂性脑缺血发作高危患者中阿司匹林与氯吡格雷联用对比单用氯吡格雷的疗效(MATCH):随机、双盲、安慰剂对照试验
Lancet. 2004;364(9431):331-7. doi: 10.1016/S0140-6736(04)16721-4.
7
Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III guidelines.近期临床试验对美国国家胆固醇教育计划成人治疗组第三次指南的影响。
Circulation. 2004 Jul 13;110(2):227-39. doi: 10.1161/01.CIR.0000133317.49796.0E.
8
Effects of an inhibitor of cholesteryl ester transfer protein on HDL cholesterol.胆固醇酯转运蛋白抑制剂对高密度脂蛋白胆固醇的影响。
N Engl J Med. 2004 Apr 8;350(15):1505-15. doi: 10.1056/NEJMoa031766.
9
Intensive versus moderate lipid lowering with statins after acute coronary syndromes.急性冠状动脉综合征后使用他汀类药物强化降脂与中度降脂的比较。
N Engl J Med. 2004 Apr 8;350(15):1495-504. doi: 10.1056/NEJMoa040583. Epub 2004 Mar 8.
10
Beneficial effects of clopidogrel combined with aspirin in reducing cerebral emboli in patients undergoing carotid endarterectomy.氯吡格雷联合阿司匹林对接受颈动脉内膜切除术患者减少脑栓塞的有益作用。
Circulation. 2004 Mar 30;109(12):1476-81. doi: 10.1161/01.CIR.0000121739.05643.E6. Epub 2004 Mar 8.