Rajamani Kumar, Chaturvedi Seemant
Comprehensive Stroke Program and Department of Neurology, Wayne State University, 8C-UHC, 4201 St. Antoine, Detroit, MI 48201, USA.
Curr Treat Options Cardiovasc Med. 2008 Apr;10(2):156-63. doi: 10.1007/s11936-008-0017-x.
Most patients with ischemic stroke or transient ischemic attack are screened for internal carotid artery stenosis. Although it is important to identify candidates for endarterectomy or stenting, the clinician must realize that most patients are not candidates for revascularization. Therefore, medical therapy remains the cornerstone of treatment. In this article, current thinking on medical therapy for carotid atherosclerosis is outlined, including aggressive use of statins, targeted blood pressure lowering, and antithrombotic therapy. Implementation of these therapies will likely reduce the need for revascularization procedures in the future.
大多数缺血性中风或短暂性脑缺血发作患者会接受颈内动脉狭窄筛查。虽然识别适合进行内膜切除术或支架置入术的患者很重要，但临床医生必须认识到，大多数患者并不适合进行血运重建。因此，药物治疗仍然是治疗的基石。本文概述了目前关于颈动脉粥样硬化药物治疗的思路，包括积极使用他汀类药物、有针对性地降低血压以及抗血栓治疗。实施这些治疗可能会减少未来血运重建手术的需求。
