Ethical issues in predictive genetic testing: a public health perspective.
作者信息
Fulda K G, Lykens K
机构信息
Department of Biostatistics, School of Public Health, University of North Texas Health Science Center, Fort Worth, TX 76107, USA.
出版信息
J Med Ethics. 2006 Mar;32(3):143-7. doi: 10.1136/jme.2004.010272.
Abstract
As a result of the increase in genetic testing and the fear of discrimination by insurance companies, employers, and society as a result of genetic testing, the disciplines of ethics, public health, and genetics have converged. Whether relatives of someone with a positive predictive genetic test should be notified of the results and risks is a matter urgently in need of debate. Such a debate must encompass the moral and ethical obligations of the diagnosing physician and the patient. The decision to inform or not will vary depending on what moral theory is used. Utilising the utilitarian and libertarian theories produces different outcomes. The principles of justice and non-maleficence will also play an important role in the decision.
摘要
相似文献
1
Ethical issues in predictive genetic testing: a public health perspective.
J Med Ethics. 2006 Mar;32(3):143-7. doi: 10.1136/jme.2004.010272.
2
Privacy and disclosure in medical genetics examined in an ethics of care.
Bioethics. 1991 Jul;5(3):212-32. doi: 10.1111/j.1467-8519.1991.tb00161.x.
3
Human need and the right of patients to privacy.
J Contemp Health Law Policy. 1997 Fall;14(1):1-21.
4
Justice and medical ethics.
Br Med J (Clin Res Ed). 1985 Jul 20;291(6489):201-2. doi: 10.1136/bmj.291.6489.201.
5
Alerting relatives about heritable risks: the limits of confidentiality.
BMJ. 2018 Apr 5;361:k1409. doi: 10.1136/bmj.k1409.
6
Ethical issues in genetic screening and antenatal diagnosis.
Clin Obstet Gynecol. 1981 Dec;24(4):1151-68. doi: 10.1097/00003081-198112000-00012.
7
Ethics, law, and medical genetics: after the human genome is mapped.
Emory Law J. 1990 Summer;39(3):747-809.
8
Genetic knowledge and third-party interests.
Camb Q Healthc Ethics. 1999 Summer;8(3):386-92. doi: 10.1017/s096318019980317x.
9
Ethical conflicts in placebo treatment.
J Adv Nurs. 1991 Aug;16(8):947-51. doi: 10.1111/j.1365-2648.1991.tb01799.x.
10
Genetics, insurance, and the ethics of genetic counseling.
Mol Genet Med. 1993;3:159-77. doi: 10.1016/b978-0-12-462003-2.50010-9.
引用本文的文献
1
Presymptomatic Screening for Risks to Children's Mental Health : Ethical Considerations from a European Focus Group Study with Mental Health Professionals.
J Bioeth Inq. 2025 Sep 15. doi: 10.1007/s11673-025-10473-0.
2
Genetic Markers of Susceptibility in Gastric Cancer: A Comprehensive Systematic Review.
Cureus. 2024 Sep 1;16(9):e68358. doi: 10.7759/cureus.68358. eCollection 2024 Sep.
3
Ethical Aspects of Human Genome Research in Sports-A Narrative Review.
Genes (Basel). 2024 Sep 18;15(9):1216. doi: 10.3390/genes15091216.
4
Whole genome sequencing in clinical practice.
BMC Med Genomics. 2024 Jan 29;17(1):39. doi: 10.1186/s12920-024-01795-w.
5
The Intersection between Pharmacogenomics and Health Equity: A Case Example.
Pharmacy (Basel). 2023 Dec 5;11(6):186. doi: 10.3390/pharmacy11060186.
6
The Role of Genetic Testing in Pediatric Renal Diseases: Diagnostic, Prognostic, and Social Implications.
Cureus. 2023 Aug 31;15(8):e44490. doi: 10.7759/cureus.44490. eCollection 2023 Aug.
7
A Social and Ethical Framework for Providing Health Information Obtained from Combining Genetics and Fitness Tracking Data.
Technol Soc. 2023 Aug;74. doi: 10.1016/j.techsoc.2023.102297. Epub 2023 Jun 16.
8
Research Participants' Preferences for Individual Results of Pharmacogenomics Research: A Case of a Ugandan HIV Research Institute.
J Empir Res Hum Res Ethics. 2023 Oct;18(4):218-232. doi: 10.1177/15562646231187434. Epub 2023 Jul 13.
9
Gender-specific counselling of patients with upper tract urothelial carcinoma and Lynch syndrome.
World J Urol. 2023 Jul;41(7):1741-1749. doi: 10.1007/s00345-023-04344-9. Epub 2023 Mar 24.
10
Economic evaluation of using polygenic risk score to guide risk screening and interventions for the prevention of type 2 diabetes in individuals with high overall baseline risk.
Front Genet. 2022 Sep 15;13:880799. doi: 10.3389/fgene.2022.880799. eCollection 2022.
本文引用的文献
1
Facing Carrie Buck.
Hastings Cent Rep. 2003 Mar-Apr;33(2):14-7.
2
"Genetic exceptionalism" in medicine: clarifying the differences between genetic and nongenetic tests.
Ann Intern Med. 2003 Apr 1;138(7):571-5. doi: 10.7326/0003-4819-138-7-200304010-00013.
3
Population screening in the age of genomic medicine.
N Engl J Med. 2003 Jan 2;348(1):50-8. doi: 10.1056/NEJMra013182.
4
A general approach to genetic counseling.
Obstet Gynecol Clin North Am. 2002 Jun;29(2):265-76. doi: 10.1016/s0889-8545(02)00003-7.
5
Newborn screening as a model for population screening.
Mol Genet Metab. 2002 Apr;75(4):299-307. doi: 10.1016/S1096-7192(02)00005-7.
6
Genetics in kidney disease: how much do we want to know?
Am J Kidney Dis. 2002 Mar;39(3):637-52. doi: 10.1053/ajkd.2002.32402.
7
Ethics instruction in an issues-oriented course on public health genetics.
Health Educ Behav. 2002 Feb;29(1):43-60. doi: 10.1177/109019810202900106.
8
Laboratory standards and guidelines for population-based cystic fibrosis carrier screening.
Genet Med. 2001 Mar-Apr;3(2):149-54. doi: 10.1097/00125817-200103000-00010.
9
US employer agrees to stop genetic testing.
BMJ. 2001 Feb 24;322(7284):449.
10
Is public health ready for genetics?
Arch Pediatr Adolesc Med. 2001 Feb;155(2):117-8. doi: 10.1001/archpedi.155.2.117.
Zotero 插件