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体育人类基因组研究的伦理问题——叙事性综述。

Ethical Aspects of Human Genome Research in Sports-A Narrative Review.

机构信息

Biochemistry Department, Faculty of Physical Culture, Gdansk University of Physical Education and Sport, 80-336 Gdansk, Poland.

出版信息

Genes (Basel). 2024 Sep 18;15(9):1216. doi: 10.3390/genes15091216.

Abstract

Human genome research in sports raises complex ethical considerations regarding the intersection of genetics and athletic performance. Pursuing genetic enhancements must uphold fairness, equality, and respect for human dignity. This narrative review explores the ethical dimensions of human genome research in sports, its potential implications on athletes, and the integrity of sports. As a narrative review, this study synthesizes the existing literature and expert insights to examine the ethical aspects of human genome research in sports. This study extensively examined the current literature on genetics, sports performance, ethical concerns, human rights, and legal regulations within the European context. The literature was searched using the SPORTDiscus, Scopus, Google Scholar, and PubMed databases. Exploring human genome research in sports reveals significant ethical implications, including potential genetic discrimination, impacts on human rights, and creating a genetic underclass of athletes. There are also definite benefits surrounding genetic testing. In conclusion, this review contends that integrating ethical considerations into developing and applying genetic technologies in sports is crucial to upholding fundamental principles of fairness, equality, and respect for human dignity. It stresses the importance of open and inclusive dialogue about the potential consequences of genetic advancements on athletic performance, future generations, and the integrity of sports.

摘要

人类基因组学在体育运动中的研究引发了一系列复杂的伦理问题,涉及到遗传学和运动表现的交叉点。追求基因增强必须维护公平、平等和尊重人类尊严。本叙事性综述探讨了人类基因组学在体育运动中的伦理维度、其对运动员的潜在影响以及体育运动的完整性。作为一项叙事性综述,本研究综合了现有文献和专家观点,以检验人类基因组学在体育运动中的伦理方面。本研究广泛查阅了欧洲背景下有关遗传学、运动表现、伦理关注、人权和法律规定的现有文献。文献检索使用了 SPORTDiscus、Scopus、Google Scholar 和 PubMed 数据库。对人类基因组学在体育运动中的研究揭示了重大的伦理影响,包括潜在的基因歧视、对人权的影响以及创造运动员的基因弱势群体。同时,基因检测也有明确的好处。总之,本综述认为,将伦理考虑纳入体育运动中基因技术的开发和应用至关重要,以维护公平、平等和尊重人类尊严的基本原则。它强调了就基因进步对运动表现、后代和体育运动的完整性的潜在影响进行公开和包容的对话的重要性。

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本文引用的文献

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Genomic predictors of physical activity and athletic performance.体力活动和运动表现的基因组预测因子。
Adv Genet. 2024;111:311-408. doi: 10.1016/bs.adgen.2024.01.001. Epub 2024 Feb 15.
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The human genome as the common heritage of humanity.人类基因组是人类的共同遗产。
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