Coca Antonio, Dalfó Antonio, Esmatjes Enric, Llisterri José Luis, Ordóñez Jordi, Gomis Ramón, González-Juanatey José Ramón, Martín-Zurro Armando
Instituto de Medicina y Dermatología, Hospital Clínic, IDIBAPS, Universidad de Barcelona, Barcelona, Spain.
Med Clin (Barc). 2006 Feb 18;126(6):201-5. doi: 10.1157/13084868.
The PREVENCAT study was designed to estimate the control of the main cardiovascular risk factors (CVRF) and their treatment in a sample of population having the diagnoses of hypertension (HT), type 2 diabetes mellitus (DM2) or hypercholesterolemia (HC) who was attended by primary care physicians in Spain.
Cross-sectional study in patients with HT, DM2 and/or HC, who were consecutively recruited. We describe the treatments for HT, DM2 and HC and analyze and the association between several potential predictors and the control of these CVRF.
2,649 patients were included in the study. 95% of HT patients were under treatment, as were 84% of DM2 and 71.4% of HC patients; most common drugs were diuretics, sulphonylureas and statins, respectively. Monotherapy was more frequent than combined therapy for hypertension treatment. The frequency of HT and DM2 treatment was similar among the subgroups defined by the presence or absence of the other two diagnoses. However, HC treatment was more common in the presence of DM2 (p = 0.001). Age, previous cardiovascular disease (CVD), DM2, obesity and sedentarism were all predictors of poor blood pressure control despite drug treatment. Age, previous CVD, HT and sedentarism were predictors of poor HC control.
CVRF treatment was high although heterogeneous and not based on the best available evidence. DM2, previous CVD and obesity were associated with insufficient blood pressure control.
PREVENCAT研究旨在评估西班牙基层医疗医生所诊治的已确诊高血压（HT）、2型糖尿病（DM2）或高胆固醇血症（HC）人群样本中主要心血管危险因素（CVRF）的控制情况及其治疗情况。
对连续招募的HT、DM2和/或HC患者进行横断面研究。我们描述了HT、DM2和HC的治疗方法，并分析了几个潜在预测因素与这些CVRF控制情况之间的关联。
2649例患者纳入研究。95%的HT患者接受了治疗，DM2患者为84%，HC患者为71.4%；最常用药物分别为利尿剂、磺脲类药物和他汀类药物。高血压治疗中单一疗法比联合疗法更常见。在根据是否存在其他两种诊断定义的亚组中，HT和DM2的治疗频率相似。然而，DM2存在时HC治疗更常见（p = 0.001）。年龄、既往心血管疾病（CVD）、DM2、肥胖和久坐不动都是尽管接受药物治疗但血压控制不佳的预测因素。年龄、既往CVD、HT和久坐不动是HC控制不佳的预测因素。
CVRF治疗率较高，尽管存在异质性且并非基于最佳现有证据。DM2、既往CVD和肥胖与血压控制不充分相关。
