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接受系统治疗的中重度银屑病患者的心血管危险因素和心血管疾病。PSO-RISK,描述性研究。

Cardiovascular risk factors and cardiovascular diseases in patients with moderate to severe psoriasis under systemic treatment. PSO-RISK, descriptive study.

作者信息

Vanaclocha Francisco, Belinchón Isabel, Sánchez-Carazo José L, Rivera Raquel, Carrascosa José M, Cea-Calvo Luis, Juliá Berta, Puig Lluìs

机构信息

Dpt Dermatology, Hospital 12 de Octubre, Av de Córdoba, s/n, 28041 Madrid, Spain.

Dpt Dermatology, Hospital General Universitario, Alicante, Spain.

出版信息

Eur J Dermatol. 2014 Nov-Dec;24(6):662-9. doi: 10.1684/ejd.2014.2440.

DOI:10.1684/ejd.2014.2440
PMID:25333326
Abstract

BACKGROUND

The prevalence of cardiovascular risk factors (CVRF) in psoriasis has not been studied in large Spanish samples.

OBJECTIVE

To assess the prevalence of major CVRFs in psoriasis patients requiring systemic treatments.

MATERIAL AND METHODS

Cross-sectional study in psoriasis patients from 33 hospital dermatology offices throughout Spain. Blood pressure (BP) was measured and a fasting lab test was performed. Each CVRF was diagnosed according to the recommendations of international societies.

RESULTS

In 368 patients (mean age 48 years old, 36% women), 80.2% had at least one CVRF. The prevalence of each CVRF was similar in men and women and slightly higher in patients with psoriatic arthritis and in patients with a history of more severe disease. The percentage of patients treated with drugs to control CVRF was low (∼ 50% of those with each CVRF). A total of 20.7% had experienced some cardiovascular disease (CVD) episode.

CONCLUSION

The prevalence of CVRF was high, higher than in the general Spanish population, and 20% had already suffered CVD. However, the percentage with drug treatments for CVRF was low.

摘要

背景

尚未在大量西班牙样本中研究银屑病患者心血管危险因素(CVRF)的患病率。

目的

评估需要进行系统治疗的银屑病患者中主要CVRF的患病率。

材料与方法

对来自西班牙33家医院皮肤科门诊的银屑病患者进行横断面研究。测量血压(BP)并进行空腹实验室检查。每种CVRF均根据国际协会的建议进行诊断。

结果

在368例患者(平均年龄48岁,36%为女性)中,80.2%至少有一种CVRF。每种CVRF的患病率在男性和女性中相似,在银屑病关节炎患者和有更严重疾病史的患者中略高。使用药物控制CVRF的患者比例较低(每种CVRF患者中约50%)。共有20.7%经历过某些心血管疾病(CVD)发作。

结论

CVRF的患病率很高,高于西班牙普通人群,并且20%已经患有CVD。然而,接受CVRF药物治疗的比例较低。

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